Detry J M, Fesler R, Berckmans T, Leclercq P
Division of Cardiology, University of Louvain, Saint-Luc University Hospital, Brussels, Belgium.
Cardiovasc Drugs Ther. 1990 Aug;4 Suppl 4:841-6. doi: 10.1007/BF00051290.
Holter-detected myocardial ischemia, either painful or painless, is an important issue in the functional and prognostic evaluation of coronary patients. This paper describes one of the first attempts to reliably quantify the duration and severity of the ischemic ST-segment changes over a given period of time; the algorithm described here provides physicians with a global index of ischemia that is the total ischemic area, namely, the integral of ST-segment depression or elevation over time (expressed in mm x min). The diagnostic and prognostic power of this new index remains to be established and to be compared with the actually used simple measurements, i.e., the number and duration of ischemic events.
动态心电图检测到的心肌缺血，无论有无疼痛，都是冠心病患者功能和预后评估中的一个重要问题。本文描述了首次尝试可靠地量化给定时间段内心肌缺血性ST段改变的持续时间和严重程度；这里描述的算法为医生提供了一个缺血的总体指标，即总缺血面积，也就是ST段压低或抬高随时间的积分（以毫米×分钟表示）。这个新指标的诊断和预后能力仍有待确定，并与实际使用的简单测量方法（即缺血事件的数量和持续时间）进行比较。
