Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.
Physiology (Bethesda). 2010 Oct;25(5):280-92. doi: 10.1152/physiol.00022.2010.
Ion and water transport by the kidney is continually adjusted in response to physiological cues. Selective endocytosis and endosomal trafficking of ion transporters are increasingly appreciated as mechanisms to acutely modulate renal function. Here, we discuss emerging paradigms in this new area of investigation.
肾脏通过离子和水的运输来不断响应生理信号进行调节。离子转运体的选择性内吞作用和内体运输越来越被认为是急性调节肾功能的机制。本文讨论了该新研究领域中新兴的范例。