Faculty of Health and Social Care Sciences, Kingston University, St Georges University of London, Cranmer Terrace, London SW17 0RE, UK.
BMC Musculoskelet Disord. 2010 Oct 13;11:236. doi: 10.1186/1471-2474-11-236.
The rise in disability due to back pain has been exponential with escalating medical and societal costs. The relative contribution of individual prognostic indicators to the pattern of recovery remains unclear. The objective of this study was to determine the prognostic value of demographic, psychosocial, employment and clinical factors on outcome in patients with low back pain
A prospective cohort study with six-month follow-up was undertaken at a multidisciplinary back pain clinic in central London employing physiotherapists, osteopaths, clinical psychologists and physicians, receiving referrals from 123 general practitioners. Over a twelve-month period, 593 consecutive patients referred from general practice with simple low back pain were recruited. A baseline questionnaire was developed to elicit information on potential prognostic variables. The primary outcome measures were change in 24-item Roland Morris disability questionnaire score at six months as a measure of low back related functional disability and the physical functioning scale of the SF-36, adjusted for baseline scores.
Roland Morris scores improved by 3.8 index points (95% confidence interval 3.23 to 4.32) at six months and SF-36 physical functioning score by 10.7 points (95% confidence interval 8.36 to 12.95). Ten factors were linked to outcome yet in a multiple regression model only two remained predictive. Those with episodic rather than continuous pain were more likely to have recovered at six months (odds ratio 2.64 confidence interval 1.25 to 5.60), while those that classified themselves as non-white were less likely to have recovered (0.41 confidence interval 0.18 to 0.96).
Analysis controlling for confounding variables, demonstrated that participants showed greater improvement if their episodes of pain during the previous year were short-lived while those with Middle Eastern, North African and Chinese ethnicity demonstrated minimal improvement. The study did not support previous findings that a wide range of factors could predict outcome.
由于背痛导致的残疾人数呈指数级增长,医疗和社会成本也在不断上升。个体预后指标对康复模式的相对贡献仍不清楚。本研究的目的是确定人口统计学、心理社会、就业和临床因素对腰痛患者预后的预测价值。
在伦敦市中心的一家多学科腰痛诊所进行了一项前瞻性队列研究,该诊所由物理治疗师、整骨医生、临床心理学家和医生组成,从 123 名全科医生那里接受转诊。在 12 个月的时间里,共招募了 593 名来自全科医生的连续简单腰痛患者。制定了基线问卷,以获取潜在预后变量的信息。主要结局测量指标为 6 个月时 24 项 Roland Morris 残疾问卷评分的变化,以衡量与腰痛相关的功能残疾,以及 SF-36 的身体功能评分,根据基线评分进行调整。
Roland Morris 评分在 6 个月时改善了 3.8 个指数点(95%置信区间 3.23 至 4.32),SF-36 身体功能评分改善了 10.7 点(95%置信区间 8.36 至 12.95)。有 10 个因素与结果有关,但在多元回归模型中只有两个仍然具有预测性。那些有间歇性而不是持续性疼痛的人在 6 个月时更有可能康复(优势比 2.64,95%置信区间 1.25 至 5.60),而那些自我归类为非白色人种的人康复的可能性较小(0.41,95%置信区间 0.18 至 0.96)。
在控制混杂变量的分析中,研究表明,如果参与者在过去一年中的疼痛发作持续时间较短,则他们的病情会有更大的改善,而来自中东、北非和中国的患者则表现出最小的改善。该研究不支持以前的发现,即广泛的因素可以预测结果。