Department of Rheumatology and Immunology, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
Lupus. 2010 Oct;19(12):1430-5. doi: 10.1177/0961203310374309.
The multicultural and multilinguistic landscape in Asia poses interesting challenges in the assessment and improvement of Health-Related Quality of Life (HRQoL) in Asian patients with systemic lupus erythematosus (SLE). This article highlights some of these challenges and addresses the issue of how to improve HRQoL of these patients by: (1) framing important concepts in HRQoL in relation to the chronic relapsing nature and multisystem involvement in this condition; (2) discussing ways to improve measurement of HRQoL of SLE patients in Asia by reviewing existing HRQoL instruments (both generic (i.e. the SF-36) and disease-specific (i.e. the L-QoL, LupusQoL, SLEQoL and SLE Symptom Checklist)) and item banking; and (3) discussing approaches to improving HRQoL in SLE.
亚洲的多元文化和多语言环境给评估和改善系统性红斑狼疮（SLE）亚洲患者的健康相关生活质量（HRQoL）带来了有趣的挑战。本文重点介绍了其中的一些挑战，并探讨了如何通过以下方法来提高这些患者的 HRQoL：（1）将 HRQoL 中的重要概念与该疾病的慢性复发性和多系统受累联系起来；（2）通过回顾现有的 HRQoL 工具（通用工具，如 SF-36；疾病特异性工具，如 L-QoL、LupusQoL、SLEQoL 和 SLE 症状清单）和项目库，讨论如何改善亚洲 SLE 患者的 HRQoL 测量方法；（3）讨论改善 SLE 患者 HRQoL 的方法。
