Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, Kansas, USA.
Stroke. 2010 Dec;41(12):2908-12. doi: 10.1161/STROKEAHA.110.596064. Epub 2010 Oct 14.
Post-stroke fatigue is a common and neglected issue despite the fact that it impacts daily functions, quality of life, and has been linked with a higher mortality rate because of its association with a sedentary lifestyle. The purpose of this study was to identify the contributing factors of exertion fatigue and chronic fatigue in people post-stroke.
Twenty-one post-stroke people (12 males, 9 females; 59.5 ± 10.3 years of age; time after stroke 4.1 ± 3.5 years) participated in the study. The response variables included exertion fatigue and chronic fatigue. Participants underwent a standardized fatigue-inducing exercise on a recumbent stepper. Exertion fatigue level was assessed at rest and immediately after exercise using the Visual Analog Fatigue Scale. Chronic fatigue was measured by the Fatigue Severity Scale. The explanatory variables included aerobic fitness, motor control, and depressive symptoms measured by peak oxygen uptake, Fugl-Meyer motor score, and the Geriatric Depression Scale, respectively.
Using forward stepwise regression, we found that peak oxygen uptake was an independent predictor of exertion fatigue (P = 0.006), whereas depression was an independent predictor of chronic fatigue (P = 0.002).
Exertion fatigue and chronic fatigue are 2 distinct fatigue constructs, as identified by 2 different contributing factors.
尽管卒中后疲劳会影响日常功能、生活质量，并与久坐的生活方式有关，从而导致更高的死亡率，但它仍是一个常见且被忽视的问题。本研究旨在确定卒中后人群中易疲劳和慢性疲劳的影响因素。
21 名卒中后患者（12 名男性，9 名女性；59.5±10.3 岁；卒中后时间 4.1±3.5 年）参与了这项研究。因变量包括易疲劳和慢性疲劳。参与者在卧式踏步器上进行标准化的疲劳诱发运动。使用视觉模拟疲劳量表在休息时和运动后即刻评估易疲劳水平。慢性疲劳通过疲劳严重程度量表进行测量。解释变量分别为峰值摄氧量、Fugl-Meyer 运动评分和老年抑郁量表所测量的有氧适能、运动控制和抑郁症状。
采用逐步向前回归，我们发现峰值摄氧量是易疲劳的独立预测因素（P=0.006），而抑郁是慢性疲劳的独立预测因素（P=0.002）。
易疲劳和慢性疲劳是两种不同的疲劳结构，由两种不同的影响因素所致。
