细菌表面蛋白与疫苗。
Bacterial surface proteins and vaccines.
作者信息
Grandi Guido
机构信息
Novartis Vaccines and Diagnostics Via Fiorentina 1, 53100, Siena Italy.
出版信息
F1000 Biol Rep. 2010 May 11;2:36. doi: 10.3410/B2-36.
Abstract
Surface-associated proteins play a key role in bacterial physiology and pathogenesis and are the major targets for vaccine development. Recent advances in defining the proteins associated with, and protruding out of, bacterial cells to a high level of accuracy are substantially contributing to accelerating the process of vaccine target identification and development.
摘要
表面相关蛋白在细菌生理学和发病机制中起关键作用，是疫苗开发的主要靶点。在高精度鉴定与细菌细胞相关并突出于细菌细胞外的蛋白方面取得的最新进展，正极大地推动疫苗靶点识别和开发进程。
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