Fischer M, Romaniuk P, Gliech V, Göldner B, Hujer W
Institut für kardiovaskuläre Diagnostik des Bereiches Medizin (Charité) der Humboldt-Universität zu Berlin.
Radiol Diagn (Berl). 1990;31(6):569-80.
Since the introduction into practice in may 1986 at the Institute of Cardiovascular Diagnostics we performed 45 valvuloplasties until March 1990 in 34 children (6.2 +/- 4.9 years old) and 11 adults (29.5 +/- 9.6 years) with valvular pulmonary stenosis. The invasively obtained pressure gradient at the valve diminished from 83.4 +/- 30.7 mm Hg to 35.7 +/- 19.0 mm Hg. Intraoperative complications in three patients (short term asystole, severe bradycardia, increase of right ventricular pressure to 300 mm Hg after valvuloplasty) were controlled, but demanded the end of the intervention. No significant insufficiency of pulmonary valves after valvuloplasty was seen. 18 patients were clinically investigated 14.6 +/- 9.4 months after intervention. The late results for these patients proved the method as a long term curing treatment. According to our present results pulmonary valvuloplasty is the alternative method for valve surgery especially in critical pulmonary valve stenosis in newborns.
自1986年5月在心血管诊断研究所将该方法应用于临床实践以来，截至1990年3月，我们对34名儿童（6.2±4.9岁）和11名成人（29.5±9.6岁）的瓣膜性肺动脉狭窄患者进行了45次瓣膜成形术。瓣膜处通过侵入性获得的压力梯度从83.4±30.7毫米汞柱降至35.7±19.0毫米汞柱。3例患者出现术中并发症（短期心脏停搏、严重心动过缓、瓣膜成形术后右心室压力升至300毫米汞柱），虽经控制，但需终止手术。瓣膜成形术后未见明显肺动脉瓣关闭不全。18例患者在干预后14.6±9.4个月接受了临床检查。这些患者的远期结果证明该方法是一种长期治愈性治疗方法。根据我们目前的结果，肺动脉瓣成形术是瓣膜手术的替代方法，尤其是对于新生儿严重肺动脉瓣狭窄。
