Muschietti Jorge, McCormick Sheila
F1000 Biol Rep. 2010 Feb 24;2:15. doi: 10.3410/B2-15.
The plant hormone abscisic acid (ABA) plays a role in several aspects of plant growth and development. Understanding how this hormonal stimulus is sensed and transduced turned out to be one of the major tasks in the field of plant signaling. A series of recent papers proposed several different proteins that could receive the ABA signal and initiate the signaling cascade. The winner appears to be PYR/PYL/RCAR (PYrabactin Resistance/PYrabactin Resistance-Like/Regulatory Component of Abscisic acid Receptor) proteins, as crystal structures were recently published. The crystal structures support the idea that upon ABA binding to a PYR/PYL/RCAR protein, the activity of a phosphatase 2C, with known repressive activity on ABA signaling, is inhibited.
植物激素脱落酸（ABA）在植物生长发育的多个方面发挥作用。了解这种激素刺激是如何被感知和转导的，结果成为植物信号传导领域的主要任务之一。最近的一系列论文提出了几种不同的蛋白质，它们可能接收ABA信号并启动信号级联反应。随着最近晶体结构的发表，获胜者似乎是PYR/PYL/RCAR（抗脱落酸/类抗脱落酸/脱落酸受体调节成分）蛋白。晶体结构支持这样一种观点，即当ABA与PYR/PYL/RCAR蛋白结合时，对ABA信号传导具有已知抑制活性的磷酸酶2C的活性会受到抑制。
