Rabito Felicia A, Perry Sara, Davis W Edward, Yau C Lillian, Levetin Estelle
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street SL-18, New Orleans, LA 70112, USA.
J Allergy (Cairo). 2010;2010. doi: 10.1155/2010/510380. Epub 2010 Jun 16.
Objectives. The study's objective was to examine the relation between mold/dampness exposure and mold sensitization among residents of Greater New Orleans following Hurricane Katrina. Methods. Patients were recruited from the Allergy Clinic of a major medical facility. Any patient receiving a skin prick test for one of 24 molds between December 1, 2005 and December 31, 2008 was eligible for the study. Exposure was assessed using standardized questionnaires. Positive mold reactivity was defined as a wheal diameter >3 mm to any mold genera. Results. Approximately 57% of participants tested positive to any indoor allergen, 10% to any mold. Over half of respondents had significant home damage, 34% reported dampness/mold in their home, half engaged in renovation, and one-third lived in a home undergoing renovation. Despite extensive exposure, and multiple measures of exposure, we found no relationship between mold/dampness exposure and sensitivity to mold allergens. Conclusions. These results along with results of earlier research indicate no excess risk of adverse respiratory effects for residents living in New Orleans after the devastation of Hurricane Katrina.
目的。本研究的目的是调查卡特里娜飓风过后大新奥尔良地区居民接触霉菌/潮湿环境与霉菌致敏之间的关系。方法。从一家大型医疗机构的过敏诊所招募患者。2005年12月1日至2008年12月31日期间接受24种霉菌之一皮肤点刺试验的任何患者均符合本研究条件。使用标准化问卷评估接触情况。阳性霉菌反应性定义为对任何霉菌属的风团直径>3毫米。结果。约57%的参与者对任何室内过敏原检测呈阳性，10%对任何霉菌检测呈阳性。超过一半的受访者房屋遭受严重破坏，34%报告家中有潮湿/霉菌，一半进行了翻新，三分之一居住在正在翻新的房屋中。尽管接触广泛，且有多种接触测量方法，但我们发现接触霉菌/潮湿环境与对霉菌过敏原的敏感性之间没有关系。结论。这些结果以及早期研究结果表明，卡特里娜飓风造成破坏后，新奥尔良居民没有额外的不良呼吸影响风险。
