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异体骨 ACL 重建术治疗年轻、活跃患者:Tegner 活动水平与失败率。

Allograft anterior cruciate ligament reconstruction in the young, active patient: Tegner activity level and failure rate.

机构信息

Mississippi Sports Medicine and Orthopaedic Center, Jackson, 39202, USA.

出版信息

Arthroscopy. 2010 Dec;26(12):1593-601. doi: 10.1016/j.arthro.2010.05.014. Epub 2010 Oct 16.

Abstract

PURPOSE

The purpose was to analyze outcomes of nonirradiated, fresh-frozen bone-patellar tendon-bone (BPTB) allograft anterior cruciate ligament (ACL) reconstruction in patients aged under 40 years with regard to activity level (Tegner score).

METHODS

Between 1993 and 2005, 111 patients, aged under 40 years, underwent primary, nonirradiated, fresh-frozen BPTB allograft ACL reconstruction and were retrospectively reviewed. Follow-up was limited to a minimum of 24 months. Patients with concomitant ligament injuries and previous surgeries were excluded. Seventy-eight patients met the inclusion criterion and were available for follow-up. Four hundred eleven patients had BPTB autograft ACL reconstructions and comprised the control group. Failure of the graft was defined as repeat ACL reconstruction because of reinjury or graft failure, 2+ Lachman (no endpoint), any pivot shift, and/or 5-mm side-to-side KT-1000 difference (MEDmetric, San Diego, CA) or greater. Initial examinations, surgical findings, and follow-up examinations were prospectively entered into a computerized relational database. The results were assessed by both objective and subjective measures.

RESULTS

High-activity allograft patients had a 2.6- to 4.2-fold increase in the probability of graft failure compared with low-activity BPTB allograft patients and low- and high-activity BPTB autograft patients. Patients undergoing BPTB autograft reconstruction reported significantly fewer problems on a visual analog scale and scored significantly higher on the postoperative Tegner activity scale than patients undergoing allograft reconstruction.

CONCLUSIONS

The active allograft group is 2.6 to 4.2 times more likely to fail compared with low-activity allografts and low- and high-activity autografts. We conclude that fresh-frozen BPTB allografts should not be used in young patients who have a high Tegner activity score because of their higher risk of failure.

LEVEL OF EVIDENCE

Level III, retrospective comparative study.

摘要

目的

分析年龄在 40 岁以下的患者中,非照射、新鲜冷冻骨-髌腱-骨(BPTB)同种异体移植物前交叉韧带(ACL)重建的结果,重点关注活动水平(Tegner 评分)。

方法

1993 年至 2005 年间,对 111 例年龄在 40 岁以下的患者进行了初次、非照射、新鲜冷冻 BPTB 同种异体 ACL 重建,并进行了回顾性研究。随访时间至少为 24 个月。排除伴有其他韧带损伤和既往手术的患者。符合纳入标准并可进行随访的患者有 78 例。411 例患者接受了 BPTB 自体移植物 ACL 重建,作为对照组。移植物失败定义为因再次损伤或移植物失败而再次进行 ACL 重建、2+Lachman(无终点)、任何前抽屉试验和/或 5mm 侧方间隙 KT-1000 差值(MEDmetric,圣地亚哥,CA)或更大。初始检查、手术发现和随访检查均前瞻性地输入计算机化的关系型数据库。通过客观和主观指标对结果进行评估。

结果

高活动同种异体移植物患者发生移植物失败的概率是低活动 BPTB 同种异体移植物患者的 2.6-4.2 倍,也是低活动和高活动 BPTB 自体移植物患者的 2.6-4.2 倍。接受 BPTB 自体移植物重建的患者在视觉模拟评分上报告的问题明显较少,术后 Tegner 活动评分明显高于接受同种异体移植物重建的患者。

结论

与低活动同种异体移植物和低活动及高活动自体移植物相比,活动同种异体移植物组发生失败的可能性要高 2.6 到 4.2 倍。我们的结论是,对于活动水平较高的年轻患者,不应使用新鲜冷冻 BPTB 同种异体移植物,因为它们的失败风险较高。

证据等级

III 级,回顾性比较研究。

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