Division of Pediatric Infectious Diseases, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, 3901 Beaubien Blvd., Detroit, MI 48201, USA.
Indian J Pediatr. 2011 Feb;78(2):192-204. doi: 10.1007/s12098-010-0258-z. Epub 2010 Oct 16.
We have sufficient knowledge and unprecedented access to global resources to dramatically reduce the transmission of HIV-1 from mother to children worldwide. Most transmission occurs during delivery and after birth through breastfeeding. For this reason, efforts to interrupt transmission have focused on peripartum period and safe infant feeding. This includes the use of antiretroviral therapy, elective cesarean section, avoidance of breastfeeding, and exclusive breastfeeding. This review summarizes recent studies and new international development on the prevention of mother-to-child HIV transmission. Prevention of mother-to-child transmission of HIV should now be integrated as part of basic maternal and child health services.
我们已经掌握了足够的知识,并以前所未有的方式获取了全球资源,从而可以大大减少全球范围内 HIV-1 的母婴传播。大多数传播发生在分娩期间和出生后通过母乳喂养期间。因此,为了阻断传播,我们一直致力于围产期和婴儿喂养安全。这包括使用抗逆转录病毒疗法、选择性剖宫产、避免母乳喂养和纯母乳喂养。这篇综述总结了最近关于预防母婴 HIV 传播的研究和新的国际发展。预防母婴 HIV 传播现在应该作为基本母婴保健服务的一部分得到整合。