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中国 G 群链球菌分离株对抗菌药物的耐药性的流行情况及机制。

Prevalence and mechanism of resistance to antimicrobial agents in group G streptococcal isolates from China.

机构信息

Department of Microbiology and Immunology, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing, China.

出版信息

Antimicrob Agents Chemother. 2011 Jan;55(1):402-4. doi: 10.1128/AAC.01106-10. Epub 2010 Oct 18.

DOI:10.1128/AAC.01106-10
PMID:20956590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3019673/
Abstract

Eighty group G streptococcal stains were collected from Chinese children. Susceptibility testing was done by a double-dilution and a disk diffusion method. PCR was used to test drug-resistant genes, and the χ(2) test and definite probability methods were used to test for statistically significant differences among the three groups. Thirty-four isolates (42.5%) showed resistance to erythromycin. There are differences between the resistance characteristics of group G streptococci from different regions of China.

摘要

从中国儿童中收集了 80 株 G 组链球菌菌株。采用双稀释法和纸片扩散法进行药敏试验。PCR 用于检测耐药基因,χ(2)检验和确定概率法用于检验三组之间的统计学差异。34 株(42.5%)对红霉素耐药。来自中国不同地区的 G 组链球菌的耐药特征存在差异。

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本文引用的文献

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Prevalence and mechanisms of erythromycin and clindamycin resistance in clinical isolates of beta-haemolytic streptococci of Lancefield groups A, B, C and G in Seville, Spain.西班牙塞维利亚A、B、C和G群兰氏β溶血性链球菌临床分离株中红霉素和克林霉素耐药性的发生率及机制
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mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.mefE基因对于肺炎链球菌中耐红霉素的M表型是必需的。
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