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功能性便秘的直接和间接医疗成本:一项基于人群的研究。

Direct and indirect medical costs of functional constipation: a population-based study.

机构信息

Research Center for Gastroenterology and Liver Disease, 7th floor, Taleghani Hospital, Shahid Beheshti University (MC), Evin, Tehran, Iran.

出版信息

Int J Colorectal Dis. 2011 Apr;26(4):515-22. doi: 10.1007/s00384-010-1077-4. Epub 2010 Oct 19.

DOI:10.1007/s00384-010-1077-4
PMID:20957375
Abstract

BACKGROUND

Constipation causes a large number of medical visits each year and imposes significant financial toll on healthcare systems worldwide. So the present community-based study was conducted in order to estimate attributable direct and indirect costs to functional constipation (FC) and to provide an overview of related physician visits in general population of Iran.

METHODS

From May 2006 to December 2007, a total of 19,200 adult persons (aged 16 and above) were drawn randomly in Tehran province, Iran (response rate 94%). Participants who reported any gastrointestinal symptoms (2,790 persons) were referred to assigned physicians to be questioned about symptoms of functional bowel disorders according to the Rome III criteria. Direct and indirect costs to FC were calculated. Attributable costs were reported as purchasing power parity dollars (PPP$).

RESULTS

Of the total 18,180 consenting participants in this study, 435 (2.4%) had FC according to Rome III criteria. Mean total cost of constipation per person was 146.84 PPP$, of which 128.68 PPP$ was related to direct costs and 18.16 PPP$ to indirect costs. Higher educated persons (189.75 PPP$), those above 64 years of age (373.42 PPP$), subjects with BMI of less than 18.5 kg/m(2) (510.84 PPP$), and widowed persons (258.50 PPP$) had the highest costs.

CONCLUSIONS

This study determined that although the economic burden of FC does not seem to be substantial in comparison to other major health problems, it still exacts a substantial toll on the health system for two reasons: chronicity and ambiguity of symptoms.

摘要

背景

便秘每年导致大量就诊,给全球卫生保健系统带来巨大经济负担。因此,开展本项以社区为基础的研究,旨在估算功能性便秘(FC)的直接和间接归因经济负担,并概述伊朗普通人群中与便秘相关的就诊情况。

方法

2006 年 5 月至 2007 年 12 月,在伊朗德黑兰省随机抽取了 19200 名(年龄 16 岁及以上)成年人(应答率为 94%)。报告有任何胃肠道症状的参与者(2790 人)被转介给指定医生,根据罗马 III 标准询问功能性肠病的症状。计算 FC 的直接和间接成本。归因成本以购买力平价美元(PPP$)报告。

结果

在这项研究的 18180 名同意参与者中,435 人(2.4%)根据罗马 III 标准患有 FC。每人便秘的总费用为 146.84 PPP$,其中 128.68 PPP$与直接费用有关,18.16 PPP$与间接费用有关。文化程度较高的人(189.75 PPP$)、64 岁以上的人(373.42 PPP$)、BMI 小于 18.5 kg/m2 的人(510.84 PPP$)和丧偶的人(258.50 PPP$)费用最高。

结论

本研究表明,尽管与其他主要健康问题相比,FC 的经济负担似乎并不高,但由于其症状的慢性和模糊性,它仍对卫生系统造成重大影响。

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