Service de neurologie, Hopital Henri Mondor, Creteil, and INSERM UG21, Faculte de Medecine Paris XII, Creteil, France.
Cogn Neuropsychol. 2003 Mar 1;20(2):163-88. doi: 10.1080/02643290242000907.
We report the case of DPI, an aphasic patient who shows a phonological impairment in production that spares certain syntactic and semantic categories. On a picture naming task, he produces mostly phono-logical paraphasias, and the probability of producing a correct response depends on the frequency and length of the target word. This deficit occurs in the presence of spared ability to find the grammatical gender of the items that he cannot name, intact conceptual knowledge, and very good reading and word repetition. Therefore, we conclude that DPI's deficit is restricted to the phonological retrieval of a correctly selected lexical entry. However, production errors are not uniform across semantic and syntactic domains. Numerals and names of days and months are totally spared compared to matched controls. In addition, abstract nouns and verbs are significantly less affected than concrete nouns, even when variables affecting phonological retrieval (frequency, length, syllabic structure) are controlled for. This suggests that a functional organisation in terms of semantic and syntactic variables exists at the level of phonological retrieval. We discuss these findings in light of current models of speech production.
我们报告了 DPI 的病例，他是一位失语症患者，在言语产生中表现出语音障碍，但某些句法和语义范畴不受影响。在图片命名任务中，他主要产生语音错语，而产生正确反应的概率取决于目标词的频率和长度。在这种情况下，他能够找到无法命名的项目的语法性别，概念知识完整，阅读和单词重复能力非常好。因此，我们得出结论，DPI 的缺陷仅限于正确选择词汇条目后的语音检索。然而，生产错误并不是跨语义和句法领域均匀分布的。与匹配的对照组相比，数字、星期和月份的名称完全不受影响。此外，与具体名词相比，抽象名词和动词受影响的程度要小得多，即使控制了影响语音检索的变量（频率、长度、音节结构）。这表明在语音检索层面上存在语义和句法变量的功能组织。我们根据当前的言语产生模型讨论了这些发现。
