Abraham K P, Reddy V, Gattuso P
Department of Pathology, Loyola University Medical Center, Maywood, IL 60153.
Am J Cardiovasc Pathol. 1990;3(3):195-8.
Cardiac involvement by metastatic neoplasms is relatively uncommon and usually occurs with widely disseminated disease. Ninety-five cases with cardiac metastases from autopsies performed over a 14-year period (1974-1987) at Loyola University Medical Center are reviewed. During this period, 3314 autopsies were performed with an average annual autopsy rate of 35%. In 806 (24.3%), a malignant disease was found, and in 95 (11.8%), there was cardiac involvement by tumor. The most common malignancies encountered in order of decreasing frequency were lung, lymphoma, breast, leukemia, stomach, melanoma, liver, and colon. Although the percentage of cardiac metastasis compares favorably with previous reports in the literature, an identical rate was present during both halves of the 14-year period studied. Improved diagnostic capabilities and treatment protocols in recent years have apparently not significantly affected the incidence, distribution, or patterns of metastatic spread to the heart.
转移性肿瘤累及心脏相对少见，通常发生于疾病广泛播散时。回顾了在1974年至1987年的14年间，洛约拉大学医学中心进行的95例尸检中有心脏转移的病例。在此期间，共进行了3314例尸检，年平均尸检率为35%。在806例（24.3%）中发现了恶性疾病，其中95例（11.8%）有肿瘤累及心脏。按频率递减顺序，最常见的恶性肿瘤依次为肺癌、淋巴瘤、乳腺癌、白血病、胃癌、黑色素瘤、肝癌和结肠癌。虽然心脏转移的百分比与文献中先前的报道相比情况较好，但在研究的14年期间的前半段和后半段，该比例相同。近年来诊断能力和治疗方案的改进显然并未显著影响转移至心脏的发生率、分布或模式。
