Banks S E, Brown L S, Ajuluchukwu D
Division of Evaluation and Medical Affairs, Addiction Research and Treatment Corporation, Brooklyn, NY 11201.
J Addict Dis. 1991;10(3):15-23. doi: 10.1300/J069v10n03_03.
Heterosexual transmission of HIV infection is closely linked with intravenous drug use. This study investigated the sexual behaviors of intravenous drug users (IVDUs) in New York City. In 1986, 284 IVDUs were recruited from newly enrolled patients in methadone treatment clinics. A questionnaire asking for information on sexual behaviors was administered and sera were collected and tested by ELISA and Western Blot techniques. Associations between behavioral data and HIV serology were evaluated using univariate methods of analysis. HIV infection was significantly associated with age (p = 0.01). Subjects not claiming prostitution were also significantly more likely to be infected (p = 0.01). Subjects reporting condom use and oral sex had lower infectivity rates. Higher infection rates were observed in subjects reporting anal sex and homosexual or bisexual sexual behavior. The findings of this study suggest that greater efforts to isolate those sexual behaviors that are predictors or correlates of heterosexual transmission of HIV infection is much needed in order to design behavioral interventions that will effectively curtail the spread of this virus.
艾滋病毒感染的异性传播与静脉注射吸毒密切相关。本研究调查了纽约市静脉注射吸毒者（IVDUs）的性行为。1986年，从美沙酮治疗诊所新登记的患者中招募了284名静脉注射吸毒者。发放了一份询问性行为信息的问卷，并采集血清，采用酶联免疫吸附测定（ELISA）和免疫印迹技术进行检测。使用单变量分析方法评估行为数据与艾滋病毒血清学之间的关联。艾滋病毒感染与年龄显著相关（p = 0.01）。未声称从事过性交易的受试者感染的可能性也显著更高（p = 0.01）。报告使用避孕套和口交的受试者感染率较低。报告肛交以及同性恋或双性恋性行为的受试者感染率较高。本研究结果表明，为了设计能够有效遏制这种病毒传播的行为干预措施，亟需加大力度找出那些可预测艾滋病毒异性传播或与之相关的性行为。
