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百日咳博德特氏菌在液体营养培养基中培养期间的抗原活性

[Antigenic activity of Bordetella pertussis during cultivation in liquid nutrient media].

作者信息

Miriasova L V, Moshiashvili I Ia, Basnak'ian I A, Sergeev V V, Zaporozhtsev L N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Jun(6):31-6.

PMID:209647
Abstract

The authors studied the antigenic activity of Bordetella pertussis during stab cultivation. For the first time there were revealed changes (oscillations) of antigenic activity: formation of 3 peaks of which the middle was the highest. A possibility of improving the quality of pertussis vaccine by using biomass at the height of the peak was experimentally founded.

摘要

作者研究了百日咳博德特氏菌在穿刺培养过程中的抗原活性。首次发现了抗原活性的变化(波动):形成了3个峰值,其中中间的峰值最高。通过实验证实了利用处于峰值高度的生物量来提高百日咳疫苗质量的可能性。

相似文献

1
[Antigenic activity of Bordetella pertussis during cultivation in liquid nutrient media].百日咳博德特氏菌在液体营养培养基中培养期间的抗原活性
Zh Mikrobiol Epidemiol Immunobiol. 1978 Jun(6):31-6.
2
[A comparative analysis of the antigenic complexes isolated from synthetic and semisynthetic media for the cultivation of Bordetella pertussis].[从用于培养百日咳博德特氏菌的合成和半合成培养基中分离出的抗原复合物的比较分析]
Zh Mikrobiol Epidemiol Immunobiol. 1995 Mar-Apr(2):87-92.
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[The expression of Bordetella pertussis protective antigens during bacterial multiplication on a medium with a fixed chemical composition].[百日咳博德特氏菌保护性抗原在化学成分固定的培养基上细菌繁殖过程中的表达]
Zh Mikrobiol Epidemiol Immunobiol. 1997 Mar-Apr(2):47-50.
4
[An acellular pertussis vaccine based on the natural complex of antigens isolated from the supernatant of a synthetic culture medium].
Zh Mikrobiol Epidemiol Immunobiol. 1997 May-Jun(3):67-70.
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Disruption of Bordetella pertussis in the Ribi cell fractionator. 1. Effect of different pressures.百日咳博德特氏菌在瑞比细胞匀浆器中的破碎。1. 不同压力的影响。
Can J Microbiol. 1971 Sep;17(9):1169-74. doi: 10.1139/m71-186.
6
Bordetella pertussis serotypes in Canada.加拿大的百日咳博德特氏菌血清型
Can Med Assoc J. 1978 Oct 7;119(7):722-4.
7
Quantification of cell-associated and free antigens in Bordetella pertussis suspensions by antigen binding ELISA.通过抗原结合酶联免疫吸附测定法对百日咳博德特氏菌悬液中细胞相关抗原和游离抗原进行定量分析。
J Immunoassay. 1997 Aug;18(3):267-84. doi: 10.1080/01971529708005819.
8
[Cultivation of Bordetella pertussis in liquid semisynthetic nutrient media with ion-exchange resins].
Zh Mikrobiol Epidemiol Immunobiol. 1981 Oct(10):64-7.
9
[Improved technology of culturing Bordetella pertussis based on a study of the kinetics of the process].基于对百日咳博德特氏菌培养过程动力学的研究改进培养技术
Zh Mikrobiol Epidemiol Immunobiol. 1983 Oct(10):20-5.
10
Role of the genetics and physiology of Bordetella pertussis in the production of vaccine and the study of host-parasite relationships in pertussis.百日咳博德特氏菌的遗传学和生理学在疫苗生产及百日咳宿主-寄生虫关系研究中的作用。
Adv Appl Microbiol. 1976;20:27-42. doi: 10.1016/s0065-2164(08)70107-2.