Miriasova L V, Moshiashvili I Ia, Basnak'ian I A, Sergeev V V, Zaporozhtsev L N
Zh Mikrobiol Epidemiol Immunobiol. 1978 Jun(6):31-6.
The authors studied the antigenic activity of Bordetella pertussis during stab cultivation. For the first time there were revealed changes (oscillations) of antigenic activity: formation of 3 peaks of which the middle was the highest. A possibility of improving the quality of pertussis vaccine by using biomass at the height of the peak was experimentally founded.
作者研究了百日咳博德特氏菌在穿刺培养过程中的抗原活性。首次发现了抗原活性的变化(波动):形成了3个峰值,其中中间的峰值最高。通过实验证实了利用处于峰值高度的生物量来提高百日咳疫苗质量的可能性。