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多囊卵巢综合征患者精神障碍的患病率。

Prevalence of psychiatric disorders in patients with polycystic ovary syndrome.

机构信息

Panic and Respiration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, INCT Translational Medicine (CNPq), Rio de Janeiro 79020-011, Brazil.

出版信息

Compr Psychiatry. 2010 Nov-Dec;51(6):599-602. doi: 10.1016/j.comppsych.2010.02.009. Epub 2010 Mar 29.

Abstract

OBJECTIVE

To investigate the prevalence of psychiatric disorders among women in ambulatory treatment for polycystic ovary syndrome (PCOS) and to correlate its clinical and demographic aspects with mental disorders.

METHODOLOGY

Seventy-two patients in ambulatory treatment at the Endocrinal and Gynaecological Institute of the Federal University of Rio de Janeiro were evaluated using Diagnostic and Statistical Manual for Mental Disorders, Fourth Edition criteria by means of MINI (Mini International Neuropsychiatric Interview, version 4.4). Polycystic ovary syndrome was confirmed according to the ultrasonographic criteria of Adams and by clinical parameters.

RESULTS

Forty-one patients (57%) presented at least one psychiatric diagnosis. Among them, the prevalence of mood disorder reached 78%. The most prevalent diagnostics were major depression (26.4%) and bipolar disorder (11.1%).

CONCLUSION

A high prevalence of mental disorders was observed, especially major depression and bipolar disorder. The data obtained regarding the relationship between PCOS and mood disorders in a Brazilian sample is in accordance with recent research findings in the same area.

摘要

目的

调查门诊多囊卵巢综合征(PCOS)女性患者中精神障碍的患病率,并将其临床和人口统计学特征与精神障碍相关联。

方法

对 72 名在里约热内卢联邦大学内分泌与妇科研究所接受门诊治疗的患者使用 MINI(Mini International Neuropsychiatric Interview,第 4.4 版)进行了《精神障碍诊断与统计手册》第四版标准的评估。多囊卵巢综合征根据 Adams 的超声标准和临床参数来确认。

结果

41 名患者(57%)至少存在一种精神诊断。其中,心境障碍的患病率达到 78%。最常见的诊断是重性抑郁障碍(26.4%)和双相障碍(11.1%)。

结论

观察到精神障碍的高患病率,尤其是重性抑郁障碍和双相障碍。在巴西样本中获得的关于 PCOS 与心境障碍之间关系的数据与该领域的最新研究结果一致。

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