Shele Grei, Genkil Jessica, Speelman Diana
Department of Biochemistry, Lake Erie College of Osteopathic Medicine, Erie, PA 16509, USA.
J Funct Morphol Kinesiol. 2020 May 31;5(2):35. doi: 10.3390/jfmk5020035.
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that is characterized by menstrual irregularity and elevated serum androgens, and is often accompanied by insulin resistance. The etiology of PCOS is unknown. Lifestyle interventions and weight loss, where appropriate, remain first-line treatments for women with PCOS. Regular physical activity is recommended for women with PCOS to maintain a healthy weight and cardiovascular fitness.
To review the evidence for the impact of various exercise interventions on hormone levels in women with PCOS.
A systematic review of original studies indexed in PubMed that utilized an exercise intervention in women with PCOS and reported hormone values pre- and post-intervention. Studies in which the effects of the exercise intervention could be determined were included.
Vigorous aerobic exercise improves insulin measures in women with PCOS. Resistance or strength training may improve androgen levels, though additional studies are warranted. Studies with yoga are limited but suggest improvements in androgens. Limited information is available on the impact of exercise on adipokines and anti-Müllerian hormone, warranting further investigation.
Recommended guidelines for women with PCOS include vigorous aerobic exercise and resistance training to improve measures of insulin sensitivity and androgen levels.
多囊卵巢综合征（PCOS）是一种常见的内分泌紊乱疾病，其特征为月经不规律以及血清雄激素水平升高，且常伴有胰岛素抵抗。PCOS的病因尚不清楚。生活方式干预和适当的体重减轻仍是PCOS女性的一线治疗方法。建议PCOS女性进行规律的体育活动以维持健康体重和心血管健康。
综述各种运动干预对PCOS女性激素水平影响的证据。
对PubMed中索引的原始研究进行系统综述，这些研究对PCOS女性采用了运动干预，并报告了干预前后的激素值。纳入能够确定运动干预效果的研究。
剧烈有氧运动可改善PCOS女性的胰岛素指标。抗阻或力量训练可能会改善雄激素水平，不过仍需更多研究。关于瑜伽的研究有限，但表明对雄激素有改善作用。关于运动对脂肪因子和抗抗抗苗勒管激素影响的信息有限，有待进一步研究。
针对PCOS女性的推荐指南包括进行剧烈有氧运动和抗阻训练，以改善胰岛素敏感性指标和雄激素水平。
