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双相 II 障碍和复发性短暂抑郁患者的气质和性格。

Temperament and character in patients with bipolar II disorder and recurrent brief depression.

机构信息

Division of Clinical Neurosciences, Department of Neuropsychiatry and Psychosomatic Medicine, Oslo University Hospital-Rikshospitalet, Oslo, Norway.

出版信息

Compr Psychiatry. 2010 Nov-Dec;51(6):607-17. doi: 10.1016/j.comppsych.2010.03.003. Epub 2010 Apr 24.

DOI:10.1016/j.comppsych.2010.03.003
PMID:20965308
Abstract

OBJECTIVES

We compared the temperament and character profiles of 21 patients with bipolar II disorder, 40 patients with recurrent brief depression (RBD; at least monthly depressive episodes meeting the diagnostic criteria for major depressive episode except for duration that is less than 2 weeks, typically 2-3 days, without fixed relation to menstrual cycle) of which 21 had no history of hypomania and 19 had experienced hypomanic episodes, and 21 age- and sex-matched controls.

METHODS

Assessments included the Montgomery-Åsberg Depression Rating Scale, Hypomania Checklist, and Temperament and Character Inventory-125. Patients with cluster A and B personality disorders were excluded.

RESULTS

Bipolar II and RBD patients had higher harm avoidance (HA) and lower self-directedness (SD) compared with controls. Excluding panic disorder comorbidity effaced this difference in HA and SD (bipolar II only) and harm avoidance. No other differences were found.

CONCLUSIONS

In this first study comparing personality profiles of patients with bipolar II vs RBD, when controlling for confounders, neither bipolar II nor RBD patients differed significantly from healthy controls. The lower SD scores among RBD patients may reflect sampling bias (a higher rate of Axis 2 cluster C disorders).

摘要

目的

我们比较了 21 例双相情感障碍患者、40 例复发性短暂性抑郁(RBD;至少每月出现符合重性抑郁发作诊断标准的抑郁发作,但持续时间少于 2 周,通常为 2-3 天,与月经周期无固定关系)患者的气质和性格特征,其中 21 例无轻躁狂病史,19 例有轻躁狂发作,以及 21 名年龄和性别匹配的对照组。

方法

评估包括蒙哥马利-阿斯伯格抑郁评定量表、轻躁狂检查表和气质与性格问卷-125。排除具有 A 型和 B 型人格障碍的患者。

结果

与对照组相比,双相情感障碍 II 型和 RBD 患者的回避伤害(HA)较高,自我导向性(SD)较低。排除惊恐障碍共病后,HA 和 SD(仅双相情感障碍)以及回避伤害的差异消失。未发现其他差异。

结论

在比较双相情感障碍 II 型与 RBD 患者的人格特征的第一项研究中,当控制混杂因素时,双相情感障碍 II 型或 RBD 患者与健康对照组无显著差异。RBD 患者的 SD 评分较低可能反映了抽样偏差(更高的轴 2 集群 C 障碍率)。

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