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睫状体少突胶质细胞瘤：一例独特病例报告并文献复习。

Oligodendroglioma of the ciliary body: a unique case report and the review of literature.

机构信息

Department of life and engineering, Harbin Institute of Technology, Harbin, China.

出版信息

BMC Cancer. 2010 Oct 23;10:579. doi: 10.1186/1471-2407-10-579.

DOI:10.1186/1471-2407-10-579
PMID:20969790
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2972288/
Abstract

BACKGROUND

To date, there is no report in the international literature of an oligodendroglioma of the ciliary body, nor is there an analysis of the possible origins of this lesion.

CASE PRESENTATION

Here we report on a 52-year-old man admitted to our hospital with a ciliary body tumor revealed by clinical examination and ultrasound, computed tomography and magnetic resonance imaging studies. Following enucleation, pathological and immunohistochemical analyses were performed. Postoperative histopathological staining results included OLIGO-2(+) and GFAP(-), leading to a pathological diagnosis of oligodendroglioma of the ciliary body in the right eye (WHO grade II).

CONCLUSIONS

Since malignant gliomas derive from transformed neural stem cells, the presence of oligodendroglioma in the ciliary body supports the hypothesis that gliomas can occur wherever neural stem cells exist. Tumors of the ciliary body derived from oligodendrocytes are difficult to diagnose; pathological analyses are essential.

摘要

背景

迄今为止，国际文献中尚无睫状体少突胶质细胞瘤的报道，也没有对该病变的可能起源进行分析。

病例报告

本研究报告了一例 52 岁男性病例，因临床检查、超声、计算机断层扫描和磁共振成像研究发现睫状体肿瘤而就诊。行眼球摘除术后，行病理和免疫组织化学分析。术后组织病理学染色结果包括 OLIGO-2(+)和 GFAP(-)，病理诊断为右眼睫状体少突胶质细胞瘤（WHO 分级 II 级）。

结论

由于恶性神经胶质瘤来源于转化的神经干细胞，因此睫状体中出现少突胶质细胞瘤支持这样一种假说，即神经胶质瘤可发生于任何存在神经干细胞的部位。源自少突胶质细胞的睫状体肿瘤难以诊断；病理分析至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/9905410da4f9/1471-2407-10-579-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/14d3d53629db/1471-2407-10-579-1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/02c92d918d8d/1471-2407-10-579-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/79add8896a07/1471-2407-10-579-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/9905410da4f9/1471-2407-10-579-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/14d3d53629db/1471-2407-10-579-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/7e8826381d0a/1471-2407-10-579-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/e3ab8ee8ae28/1471-2407-10-579-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/062bf05802b2/1471-2407-10-579-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/02c92d918d8d/1471-2407-10-579-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/79add8896a07/1471-2407-10-579-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b5/2972288/9905410da4f9/1471-2407-10-579-7.jpg

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