斑马鱼中的运动、技术和发现。
Movement, technology and discovery in the zebrafish.
机构信息
Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA.
出版信息
Curr Opin Neurobiol. 2011 Feb;21(1):110-5. doi: 10.1016/j.conb.2010.09.011. Epub 2010 Oct 20.
Abstract
Zebrafish provide unique opportunities for optogenetic studies of behavior. Here, we review the most recent work using optogenetic and imaging approaches to study the neuronal circuits controlling movements in the transparent zebrafish. Specifically, we focus on what we have learned from zebrafish about neuronal migration, network formation and behavioral control, and what the future may hold.
摘要
斑马鱼为行为的光遗传学研究提供了独特的机会。在这里，我们回顾了最近使用光遗传学和成像方法研究控制透明斑马鱼运动的神经元回路的工作。具体来说，我们专注于从斑马鱼身上了解到的关于神经元迁移、网络形成和行为控制的知识，以及未来可能的发展方向。
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本文引用的文献
1
Circuit neuroscience in zebrafish.斑马鱼的电路神经科学。
Curr Biol. 2010 Apr 27;20(8):R371-81. doi: 10.1016/j.cub.2010.02.039.
2
Roles for multifunctional and specialized spinal interneurons during motor pattern generation in tadpoles, zebrafish larvae, and turtles.多功能和特化脊髓中间神经元在蝌蚪、斑马鱼幼体和海龟运动模式生成过程中的作用。
Front Behav Neurosci. 2010 Jun 28;4:36. doi: 10.3389/fnbeh.2010.00036. eCollection 2010.
3
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing.一种光门控、钾离子选择性谷氨酸受体，可用于光抑制神经元放电。
Nat Neurosci. 2010 Aug;13(8):1027-32. doi: 10.1038/nn.2589. Epub 2010 Jun 27.
4
Prickle1b mediates interpretation of migratory cues during zebrafish facial branchiomotor neuron migration.Prickle1b 介导斑马鱼面部运动神经元迁移过程中对迁移信号的解读。
Dev Dyn. 2010 Jun;239(6):1596-608. doi: 10.1002/dvdy.22283.
5
Optogenetic localization and genetic perturbation of saccade-generating neurons in zebrafish.在斑马鱼中通过光遗传学定位和遗传干扰眼球跳动生成神经元。
J Neurosci. 2010 May 19;30(20):7111-20. doi: 10.1523/JNEUROSCI.5193-09.2010.
6
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Nat Neurosci. 2010 Jun;13(6):673-9. doi: 10.1038/nn.2547. Epub 2010 May 9.
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8
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J Neurosci. 2010 Feb 24;30(8):3048-57. doi: 10.1523/JNEUROSCI.6201-09.2010.
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