Chimpanzee Sanctuary & Wildlife Conservation Trust, PO Box 884, Entebbe, Uganda.
Virus Res. 2011 Jan;155(1):372-5. doi: 10.1016/j.virusres.2010.10.017. Epub 2010 Oct 21.
Little is known about Hepatitis B Virus (HBV) infections in chimpanzees. Therefore, we investigated the prevalence of chimpanzee HBV (chHBV) infections in captive, wild born chimpanzees in the sanctuary on Ngamba Island, Uganda and one sample from a wild free ranging chimpanzee. In one third of the plasma samples (32.4%; 12/37) we detected antibodies to Hepatitis B (core) antigen. Amongst those individuals HBV DNA was detected in one captive wild born and the wild chimpanzee. In contrast to the only available earlier described HBV sequence from the subspecies Pan troglodytes schweinfurthii, there was no evidence of recombination with human HBV. Our sequences therefore are likely to present the "original" chHBV from P. t. schweinfurthii.
关于乙型肝炎病毒（HBV）在黑猩猩中的感染情况知之甚少。因此，我们调查了乌干达恩冈贝岛保护区内圈养的、野生出生的黑猩猩以及一只野生自由放养的黑猩猩中乙型肝炎（核心）抗原抗体的流行情况。在三分之一的血浆样本（32.4%；12/37）中，我们检测到了乙型肝炎抗体。在这些个体中，一只圈养的野生出生的黑猩猩和一只野生黑猩猩中检测到了 HBV DNA。与之前描述的唯一亚种 Pan troglodytes schweinfurthii 的 HBV 序列相比，没有与人类 HBV 重组的证据。因此，我们的序列可能代表了来自 P. t. schweinfurthii 的“原始”chHBV。
