Karila Laurent, Petit Aymeric, Cottencin Olivier, Reynaud Michel
Hôpital universitaire Paul-Brousse, centre d'enseignement, de recherche et de traitement des addictions, 94800 Villejuif, France.
Presse Med. 2010 Dec;39(12):1246-53. doi: 10.1016/j.lpm.2010.09.003. Epub 2010 Oct 23.
Methamphetamine is the second illicit drug used after cannabis in North America, Asia, Oceania. It also becomes a prominent part of the European drug scene, especially in East European countries such as Czech Republic and Slovakia. Methamphetamine addiction is a serious worldwide public health problem with many consequences and complications. Significant morbidity, including cardiovascular, infectious, pulmonary, dental diseases and other systems complications are associated with methamphetamine acute or chronic use. Cognitive disorders, psychotic and mood disorders have been reported. There is also substantial evidence that methamphetamine has an adverse impact on social relationships. Treatment of methamphetamine complications is primarily supportive and need a multidisciplinary approach. It can serve as a target to initiate a treatment for the addiction problem. The use of behavioral therapies and pharmacological agents are the best therapeutic approach.
甲基苯丙胺是北美、亚洲和大洋洲继大麻之后使用的第二大非法药物。它也成为欧洲毒品问题的一个突出部分,尤其是在捷克共和国和斯洛伐克等东欧国家。甲基苯丙胺成瘾是一个严重的全球性公共卫生问题,会带来许多后果和并发症。与甲基苯丙胺急性或慢性使用相关的严重发病率,包括心血管、感染、肺部、牙科疾病和其他系统并发症。已有认知障碍、精神病性和情绪障碍的报告。也有大量证据表明甲基苯丙胺对社会关系有不利影响。甲基苯丙胺并发症的治疗主要是支持性的,需要多学科方法。它可以作为启动成瘾问题治疗的一个靶点。行为疗法和药物治疗是最佳治疗方法。