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[甲基苯丙胺依赖:后果与并发症]

[Methamphetamine dependence: Consequences and complications].

作者信息

Karila Laurent, Petit Aymeric, Cottencin Olivier, Reynaud Michel

机构信息

Hôpital universitaire Paul-Brousse, centre d'enseignement, de recherche et de traitement des addictions, 94800 Villejuif, France.

出版信息

Presse Med. 2010 Dec;39(12):1246-53. doi: 10.1016/j.lpm.2010.09.003. Epub 2010 Oct 23.

DOI:10.1016/j.lpm.2010.09.003
PMID:20971608
Abstract

Methamphetamine is the second illicit drug used after cannabis in North America, Asia, Oceania. It also becomes a prominent part of the European drug scene, especially in East European countries such as Czech Republic and Slovakia. Methamphetamine addiction is a serious worldwide public health problem with many consequences and complications. Significant morbidity, including cardiovascular, infectious, pulmonary, dental diseases and other systems complications are associated with methamphetamine acute or chronic use. Cognitive disorders, psychotic and mood disorders have been reported. There is also substantial evidence that methamphetamine has an adverse impact on social relationships. Treatment of methamphetamine complications is primarily supportive and need a multidisciplinary approach. It can serve as a target to initiate a treatment for the addiction problem. The use of behavioral therapies and pharmacological agents are the best therapeutic approach.

摘要

甲基苯丙胺是北美、亚洲和大洋洲继大麻之后使用的第二大非法药物。它也成为欧洲毒品问题的一个突出部分,尤其是在捷克共和国和斯洛伐克等东欧国家。甲基苯丙胺成瘾是一个严重的全球性公共卫生问题,会带来许多后果和并发症。与甲基苯丙胺急性或慢性使用相关的严重发病率,包括心血管、感染、肺部、牙科疾病和其他系统并发症。已有认知障碍、精神病性和情绪障碍的报告。也有大量证据表明甲基苯丙胺对社会关系有不利影响。甲基苯丙胺并发症的治疗主要是支持性的,需要多学科方法。它可以作为启动成瘾问题治疗的一个靶点。行为疗法和药物治疗是最佳治疗方法。

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[Methamphetamine dependence: Consequences and complications].[甲基苯丙胺依赖:后果与并发症]
Presse Med. 2010 Dec;39(12):1246-53. doi: 10.1016/j.lpm.2010.09.003. Epub 2010 Oct 23.
2
[Current data on methamphetamine].[关于甲基苯丙胺的当前数据]
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Identifying methamphetamine users at risk for major depressive disorder: findings from the methamphetamine treatment project at three-year follow-up.识别有患重度抑郁症风险的甲基苯丙胺使用者:甲基苯丙胺治疗项目三年随访结果
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Novel medications to treat addictive disorders.治疗成瘾性疾病的新型药物。
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A case of methamphetamine use disorder treated with the antibiotic drug minocycline.一例使用抗生素药物米诺环素治疗的甲基苯丙胺使用障碍病例。
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[Mephedrone: a new synthetic drug].[甲氧麻黄酮:一种新型合成毒品]
Presse Med. 2013 Oct;42(10):1310-6. doi: 10.1016/j.lpm.2012.11.019. Epub 2013 May 10.
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A review of the clinical pharmacology of methamphetamine.甲基苯丙胺的临床药理学综述。
Addiction. 2009 Jul;104(7):1085-99. doi: 10.1111/j.1360-0443.2009.02564.x. Epub 2009 Apr 29.
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Predictors of cardiovascular response to methamphetamine administration in methamphetamine-dependent individuals.甲基苯丙胺依赖个体中甲基苯丙胺给药后心血管反应的预测因素。
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Epidemiology of methamphetamine abuse in Missouri.密苏里州甲基苯丙胺滥用的流行病学
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A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine.一项为期6个月的随访研究:认知障碍可能预示着更频繁地使用甲基苯丙胺。
Subst Abuse. 2023 May 16;17:11782218231175811. doi: 10.1177/11782218231175811. eCollection 2023.
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Adverse effects of methamphetamine on vital organs of male rats: Histopathological and immunohistochemical investigations.甲基苯丙胺对雄性大鼠重要器官的不良影响:组织病理学和免疫组织化学研究。
Iran J Basic Med Sci. 2023;26(5):549-557. doi: 10.22038/IJBMS.2023.68573.15055.
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"There's a big tag on my head": exploring barriers to treatment seeking with women who use methamphetamine in Sydney, Australia.
“我头上有个大标签”:在澳大利亚悉尼探索使用冰毒的女性寻求治疗的障碍。
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Thymoquinone abrogates methamphetamine-induced striatal neurotoxicity and hyperlocomotor activity in mice.百里醌可消除甲基苯丙胺诱导的小鼠纹状体神经毒性和运动亢进。
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Pharmacological Treatment of Methamphetamine/Amphetamine Dependence: A Systematic Review.甲基苯丙胺/苯丙胺依赖的药物治疗:系统评价。
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