Department of Psychology and Neuroscience, University of Colorado at Boulder, Boulder, Colorado 80309, USA.
J Neurotrauma. 2011 Jan;28(1):21-34. doi: 10.1089/neu.2010.1515. Epub 2010 Dec 27.
Acupressure is a complementary and alternative medicine (CAM) treatment using fingertips to stimulate acupoints on the skin. Although suggested to improve cognitive function, acupressure has not been previously investigated with a controlled design in traumatic brain injury (TBI) survivors, who could particularly benefit from a non-pharmacological intervention for cognitive impairment. A randomized, placebo-controlled, single-blind design assessed the effects of acupressure (eight treatments over 4 weeks) on cognitive impairment and state of being following TBI, including assessment of event-related potentials (ERPs) during Stroop and auditory oddball tasks. It was hypothesized that active acupressure treatments would confer greater cognitive improvement than placebo treatments, perhaps because of enhanced relaxation response induction and resulting stress reduction. Significant treatment effects were found comparing pre- to post-treatment change between groups. During the Stroop task, the active-treatment group showed greater reduction in both P300 latency (p = 0.010, partial η² = 0.26) and amplitude (p = 0.011, partial η² = 0.26), as well as a reduced Stroop effect on accuracy (p = 0.008, partial η² = 0.21) than did the placebo group. Additionally, the active-treatment group improved more than did the placebo group on the digit span test (p = 0.043, Cohen's d = 0.68). Together, these results suggest an enhancement in working memory function associated with active treatments. Because acupressure emphasizes self-care and can be taught to novice individuals, it warrants further study as an adjunct treatment for TBI.
acupressure 是一种使用指尖刺激皮肤穴位的补充和替代医学 (CAM) 治疗方法。尽管有人建议 acupressure 可以改善认知功能，但之前在创伤性脑损伤 (TBI) 幸存者中，没有使用对照设计对其进行过研究，而 TBI 幸存者特别需要一种非药物干预来治疗认知障碍。一项随机、安慰剂对照、单盲设计评估了 acupressure（4 周内 8 次治疗）对 TBI 后认知障碍和状态的影响，包括在 Stroop 和听觉Oddball 任务期间评估事件相关电位 (ERP)。研究假设主动 acupressure 治疗会比安慰剂治疗带来更大的认知改善，也许是因为增强了放松反应诱导，从而减轻了压力。与安慰剂组相比，组间治疗前后的变化比较显示出了显著的治疗效果。在 Stroop 任务中，主动治疗组的 P300 潜伏期（p=0.010，部分 η²=0.26）和振幅（p=0.011，部分 η²=0.26）都有更大的降低，并且 Stroop 效应对准确性的影响也更小（p=0.008，部分 η²=0.21），而安慰剂组则没有。此外，主动治疗组在数字跨度测试上的改善比安慰剂组更大（p=0.043，Cohen's d=0.68）。这些结果表明，主动治疗与工作记忆功能的增强有关。由于 acupressure 强调自我保健，并且可以教授给新手，因此它值得进一步研究作为 TBI 的辅助治疗。
