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Building genetic scores to predict risk of complex diseases in humans: is it possible?

作者信息

Liu Simin, Song Yiqing

机构信息

Program on Genomics and Nutrition, Department of Epidemiology, University of California, Los Angeles, Los Angeles, California, USA.

出版信息

Diabetes. 2010 Nov;59(11):2729-31. doi: 10.2337/db10-1081.

DOI:10.2337/db10-1081
PMID:20980472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2963528/
Abstract
摘要

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Early identification of cardiovascular risk using genomics and proteomics.利用基因组学和蛋白质组学早期识别心血管风险。
Nat Rev Cardiol. 2010 Jun;7(6):309-17. doi: 10.1038/nrcardio.2010.53. Epub 2010 May 4.
3
Genetic heterogeneity in human disease.
评估 CYP2A6 活性生物标志物预测的加权遗传风险评分。
Addict Biol. 2020 Jan;25(1):e12741. doi: 10.1111/adb.12741. Epub 2019 Feb 27.
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Front Med. 2018 Dec;12(6):678-687. doi: 10.1007/s11684-018-0671-7. Epub 2018 Nov 16.
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EBioMedicine. 2017 Oct;24:64-75. doi: 10.1016/j.ebiom.2017.09.010. Epub 2017 Sep 13.
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Am J Respir Cell Mol Biol. 2017 Jul;57(1):35-46. doi: 10.1165/rcmb.2016-0331OC.
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