Nagaraj C, Chakrabarti N K, Narasimham M V
National Malaria Eradication Programme, Delhi.
J Commun Dis. 1990 Dec;22(4):260-3.
In view of the emergence of chloroquine resistant Plasmodium falciparum from more and more geographical areas profiling of the responses to other available antimalarials by in vitro methods have become essential. A preliminary study undertaken in two Primary Health Centres of Karnataka State, India show the presence of strains of P. falciparum resistant to chloroquine and amodiaquine. The response for amodiaquine was poor as compared to chloroquine. The isolates were, however, sensitive to mefloquine and quinine.
鉴于越来越多地理区域出现对氯喹耐药的恶性疟原虫，通过体外方法分析对其他现有抗疟药的反应已变得至关重要。在印度卡纳塔克邦的两个初级卫生中心进行的一项初步研究表明，存在对氯喹和氨酚喹耐药的恶性疟原虫菌株。与氯喹相比，氨酚喹的反应较差。然而，这些分离株对甲氟喹和奎宁敏感。
