May K L
Zakładu Immunologii Klinicznej Instytutu Gruźlicy i Chorób Płuc, Warszawie.
Pol Tyg Lek. 1990;45(42-44):861-3.
The author has found that 42% of patients with pollinosis had positive skin reactions with mugwort (Artemisia vulgaris) pollen allergens. The majority of tested patients (139 out of 187) were also allergic to grass pollens. However, hypersensitivity to mugwort pollen allergens was isolated and did not accompany grass pollen allergy. The symptoms of pollinosis appeared in this group later than in patients sensitive to grass pollen allergens only (over 21 years of age in 71%). Bronchial asthma was diagnosed in 40% of these patients and allergic skin reactions in 25%. Sensitivity to mugwort pollen allergens was accompanied by the sensitivity to pollen allergens of Graminae family of plants in 80% of cases. The author suggests that sensitivity to mugwort pollen allergens is the second most frequent cause of the pollinosis and is diagnosed too rarely. Failures of desensitization in patients sensitive to pollen allergens of Graminae family of plants may often result from coexisting sensitivity to mugwort pollen allergens as this sensitivity produces not only season but perennial clinical symptoms in nearly 50% of patients. The author discusses also botanical relations and cross-reactions in allergy to mugwort and ragweed pollen allergens.
作者发现，42%的花粉症患者对艾蒿（Artemisia vulgaris）花粉过敏原产生阳性皮肤反应。大多数受试患者（187例中的139例）也对草花粉过敏。然而，对艾蒿花粉过敏原的超敏反应是孤立的，并不伴有草花粉过敏。该组花粉症的症状出现时间比仅对草花粉过敏原敏感的患者晚（71%超过21岁）。这些患者中有40%被诊断为支气管哮喘，25%出现过敏性皮肤反应。80%的病例中，对艾蒿花粉过敏原的敏感性伴有对禾本科植物花粉过敏原的敏感性。作者认为，对艾蒿花粉过敏原的敏感性是花粉症第二常见的病因，且诊断过少。对禾本科植物花粉过敏原敏感的患者脱敏失败，往往可能是由于同时存在对艾蒿花粉过敏原的敏感性，因为这种敏感性在近50%的患者中不仅产生季节性症状，还产生常年性临床症状。作者还讨论了艾蒿和豚草花粉过敏原过敏中的植物学关系和交叉反应。
