Chen J G
Shanghai Institute of Industrial Hygiene and Occupational Disease.
Zhonghua Yu Fang Yi Xue Za Zhi. 1990 Nov;24(6):328-31.
901 male workers who have ever been exposed to the benzidine-derived dyes for more than 1 year in Shanghai leather-tanning industry, were investigated about their occupational history, smoking and drinking histories, case history of cancer, and the causes of death. The results showed that there was an excess morbidity of bladder cancer in this population, and the SIR was 273 (P = 0.05) compared with the general population of Shanghai urban. It may be noted that the excess of the bladder cancer was presented mainly in those workers whose ages of the first exposure were under 19 years old, and the bladder cancer incidence seemed to be associated positively with the cumulative duration of exposure. The survey about the smoking history did not show any obvious relationship between smoking and the development of the bladder cancer. Moreover, it was seen that a trend of excessive in incidence of the nasopharyngeal cancer and the lymphosarcoma existed in this population.
对上海市皮革鞣制行业中901名曾接触联苯胺衍生染料1年以上的男性工人进行了职业史、吸烟和饮酒史、癌症病史及死因调查。结果显示，该人群膀胱癌发病率过高，与上海市城市普通人群相比，标准化发病比（SIR）为273（P = 0.05）。值得注意的是，膀胱癌的超额发病主要出现在首次接触年龄在19岁以下的工人中，且膀胱癌发病率似乎与累积接触时长呈正相关。关于吸烟史的调查未显示吸烟与膀胱癌发病之间存在明显关联。此外，还发现该人群中鼻咽癌和淋巴肉瘤发病率有过高趋势。
