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1
Comparison of findings among residents on Michigan dairy farms and consumers of produce purchased from these farms.密歇根州奶牛场居民与从这些农场购买农产品的消费者之间的调查结果比较。
Environ Health Perspect. 1978 Apr;23:105-9. doi: 10.1289/ehp.7823105.
2
Unanticipated prevalence of symptoms among dairy farmers in Michigan and Wisconsin.密歇根州和威斯康星州奶农中症状的意外流行情况。
Environ Health Perspect. 1978 Apr;23:217-26. doi: 10.1289/ehp.7823217.
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Immunologic dysfunction among PBB-exposed Michigan dairy farmers.密歇根州接触多溴联苯的奶农的免疫功能障碍。
Ann N Y Acad Sci. 1979 May 31;320:717-28. doi: 10.1111/j.1749-6632.1979.tb56646.x.
4
Pediatric health aspects of PBBs.多溴联苯的儿童健康问题
Environ Health Perspect. 1978 Apr;23:291-4. doi: 10.1289/ehp.7823291.
5
Relation of DDE and PBB serum levels in farm residents, consumers, and Michigan Chemical Corporation employees.农场居民、消费者及密歇根化学公司员工血清中滴滴涕(DDE)和多溴联苯(PBB)水平的关系。
Environ Health Perspect. 1978 Apr;23:177-81. doi: 10.1289/ehp.7823177.
6
Investigation of the health status of Michigan chemical corporation employees.密歇根化学公司员工健康状况调查。
Environ Health Perspect. 1978 Apr;23:187-91. doi: 10.1289/ehp.7823187.
7
Liver function tests among Michigan and Wisconsin dairy farmers.密歇根州和威斯康星州奶农的肝功能测试
Environ Health Perspect. 1978 Apr;23:333-9. doi: 10.1289/ehp.7823333.
8
Cohort study of Michigan residents exposed to polybrominated biphenyls: epidemiologic and immunologic findings.密歇根州接触多溴联苯的居民队列研究:流行病学和免疫学发现。
Ann N Y Acad Sci. 1979 May 31;320:284-94. doi: 10.1111/j.1749-6632.1979.tb56611.x.
9
Impaired immune function and identification of polybrominated biphenyls (PBB) in blood compartments of exposed Michigan dairy farmers and chemical workers.密歇根州受暴露的奶农和化工工人血液成分中免疫功能受损及多溴联苯(PBB)的鉴定。
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Breast-milk monitoring to measure Michigan's contamination with polybrominated biphenyls.母乳监测以测定密歇根州多溴联苯的污染情况。
Lancet. 1978 Sep 23;2(8091):643-6. doi: 10.1016/s0140-6736(78)92758-7.

引用本文的文献

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A State of the Science Review of Human Health Effects of the Michigan Polybrominated Biphenyl Contamination after Five Decades.五十年后密歇根多溴联苯污染对人类健康影响的科学现状综述
Environ Health Perspect. 2025 Jun;133(6):66002. doi: 10.1289/EHP15012. Epub 2025 Jun 12.
2
Polybrominated biphenyls (PBBs) and prevalence of autoimmune disorders among members of the Michigan PBB registry.多溴联苯 (PBBs) 与密歇根 PBB 登记处成员自身免疫性疾病的患病率。
Environ Res. 2023 Dec 15;239(Pt 1):117312. doi: 10.1016/j.envres.2023.117312. Epub 2023 Oct 6.
3
Elimination of PBB-153; findings from a cohort of Michigan adults.消除五溴联苯醚-153;密歇根州成年人队列研究的结果。
Environ Res. 2023 Mar 1;220:115146. doi: 10.1016/j.envres.2022.115146. Epub 2022 Dec 23.
4
Breast-feeding among women exposed to polybrominated biphenyls in Michigan.密歇根州接触多溴联苯的女性的母乳喂养情况。
Environ Health Perspect. 2001 Nov;109(11):1133-7. doi: 10.1289/ehp.01109133.
5
Influence of maternal ingestion of Aroclor 1254 (PCB) or FireMaster BP-6 (PBB) on unstimulated and stimulated corticosterone levels in young rats.母体摄入多氯联苯混合物1254(PCB)或防火剂BP - 6(PBB)对幼鼠未受刺激和受刺激时皮质酮水平的影响。
Bull Environ Contam Toxicol. 1992 May;48(5):715-20. doi: 10.1007/BF00195992.
6
Unanticipated prevalence of symptoms among dairy farmers in Michigan and Wisconsin.密歇根州和威斯康星州奶农中症状的意外流行情况。
Environ Health Perspect. 1978 Apr;23:217-26. doi: 10.1289/ehp.7823217.
7
Comparative neurobehavioral study of a polybrominated biphenyl-exposed population in Michigan and a nonexposed group in Wisconsin.密歇根州多溴联苯暴露人群与威斯康星州未暴露人群的比较神经行为学研究。
Environ Health Perspect. 1978 Apr;23:199-210. doi: 10.1289/ehp.7823199.

本文引用的文献

1
Michigan's PBB Incident: Chemical Mix-Up Leads to Disaster.密歇根州多溴联苯事件:化学品混淆引发灾难。
Science. 1976 Apr 16;192(4236):240-3. doi: 10.1126/science.192.4236.240.
2
A toxic syndrome associated with the feeding of polybrominated biphenyl-contaminated protein concentrate to dairy cattle.一种与给奶牛喂食多溴联苯污染的蛋白质浓缩物相关的中毒综合征。
J Am Vet Med Assoc. 1974 Sep 1;165(5):437-9.
3
Unanticipated prevalence of symptoms among dairy farmers in Michigan and Wisconsin.密歇根州和威斯康星州奶农中症状的意外流行情况。
Environ Health Perspect. 1978 Apr;23:217-26. doi: 10.1289/ehp.7823217.
4
Comparative neurobehavioral study of a polybrominated biphenyl-exposed population in Michigan and a nonexposed group in Wisconsin.密歇根州多溴联苯暴露人群与威斯康星州未暴露人群的比较神经行为学研究。
Environ Health Perspect. 1978 Apr;23:199-210. doi: 10.1289/ehp.7823199.

密歇根州奶牛场居民与从这些农场购买农产品的消费者之间的调查结果比较。

Comparison of findings among residents on Michigan dairy farms and consumers of produce purchased from these farms.

作者信息

Lilis R, Anderson H A, Valciukas J A, Freedman S, Selikoff I J

出版信息

Environ Health Perspect. 1978 Apr;23:105-9. doi: 10.1289/ehp.7823105.

DOI:10.1289/ehp.7823105
PMID:209961
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1637456/
Abstract

Consumers who had purchased farm products from both quarantined and nonquarantined farms were examined during the cross-sectional clinical survey of 1,029 Michigan residents. Since PBB had inadvertently contaminated cattle and other farm animals, ingestion of meat, milk, eggs and other farm products was thought to have possibly resulted in significant PBB body burdens in some consumers. Findings were considered in comparison with those made among farm residents. Prevalence of symptoms in consumers of farm products from quarantined farms (CQ) was similar to that found in farmers on quarantined farms (FQ); the prevalence was lower in consumers of products from nonquarantined farms (CNQ). Liver function abnormalities were found with similar prevalence in dairy farmers and consumers. Distribution, mean and median values of PBB serum levels in consumers were found to be similar to those of dairy farmers. These results indicate that significant body burdens of PBB had been accumulated by some consumers of farm products in Michigan and that prevalence of symptoms and liver function abnormalities resembled those found among dairy farm residents.

摘要

在对1029名密歇根州居民进行的横断面临床调查中,对那些既从被隔离农场也从未被隔离农场购买过农产品的消费者进行了检查。由于多溴联苯意外污染了牛及其他农场动物,食用肉类、牛奶、鸡蛋及其他农产品被认为可能使一些消费者体内积累了大量的多溴联苯。研究结果与在农场居民中获得的结果进行了比较。来自被隔离农场的农产品消费者(CQ)的症状患病率与被隔离农场的农民(FQ)相似;来自未被隔离农场的农产品消费者(CNQ)的患病率较低。奶农和消费者的肝功能异常患病率相似。消费者体内多溴联苯血清水平的分布、均值和中位数与奶农相似。这些结果表明,密歇根州的一些农产品消费者体内积累了大量的多溴联苯,症状患病率和肝功能异常情况与奶农相似。