Omilabu S A, Olaleye O D, Aina Y, Fagbami A H
Department of Virology, College of Medicine, University of Ibadan, Nigeria.
J Hyg Epidemiol Microbiol Immunol. 1990;34(4):357-63.
A survey for West Nile Complement Fixing (CF) antibody was carried out in humans and domestic animals in Nigeria. Human sera were obtained from two communities namely Ibadan and Ogbomoso but animal sera were collected from Ibadan and Maiduguri. The overall CF antibody to West Nile virus in the two localities surveyed was 65%. Of 170 persons tested, 53% and 75% were positive in Ibadan and Ogbomoso respectively. Antibody prevalence increased with age in both communities. Tests for antibody against other flaviviruses revealed that monotypic complement fixation reactions were found frequently in young people, but broadly reacting sera were common among the older age groups. Sex distribution of West Nile CF antibody showed that 49/82 (60%) of females and 62/88 (75%) of males had West Nile CF antibody. Tests on animal sera showed that 33% contained CF antibody to West Nile virus. Prevalence of CF antibody in different animal species was 62% in camels, 4% in cattle and 0% in goats.
在尼日利亚对人类和家畜进行了西尼罗河补体结合（CF）抗体调查。人类血清取自伊巴丹和奥贡博索这两个社区，但动物血清采集自伊巴丹和迈杜古里。在所调查的两个地区，针对西尼罗河病毒的总体CF抗体为65%。在接受检测的170人中，伊巴丹和奥贡博索的阳性率分别为53%和75%。两个社区的抗体流行率均随年龄增长而升高。针对其他黄病毒的抗体检测显示，年轻人中经常发现单型补体结合反应，但在老年人群体中广泛反应的血清较为常见。西尼罗河CF抗体的性别分布显示，82名女性中有49人（60%）、88名男性中有62人（75%）具有西尼罗河CF抗体。对动物血清的检测表明，33%含有针对西尼罗河病毒的CF抗体。不同动物物种中CF抗体的流行率在骆驼中为62%，在牛中为4%，在山羊中为0%。
