Kolawole Oladipo Elijah, Kola Oloke Julius
a Department of Pure and Applied Biology (Microbiology/Virology Unit) , Ladoke Akintola University of Technology , Ogbomoso , Nigeria.
J Immunoassay Immunochem. 2015;36(6):573-8. doi: 10.1080/15321819.2015.1017105. Epub 2015 Feb 25.
A seroepidemiological study for West Nile virus was carried out in an urban and rural settlements in Ogbomoso for its IgM and IgG. Human sera was obtained and West Nile virus IgM and IgG was determined using Enzyme Linked Immunosorbent Assay technique. Out of 93 subjects tested, 19.4% and 12.9% were positive for IgG and IgM, respectively. Among the urban dwellers, 23.40% were positive for both IgG and IgM, while the rural dwellers had 15.22% for IgG and 2.17% for IgM. Test for pure antibody to West Nile virus revealed that 23.7% had the virus while 8.6% had antibodies that cross reacted for other flaviviruses. Results show that West Nile virus is circulating in Ogbomoso and its environ which might have accounted for malaria like infection in the region.
在奥格博莫索的城乡定居点开展了一项针对西尼罗河病毒的血清流行病学研究，检测其IgM和IgG。采集了人类血清，并采用酶联免疫吸附测定技术测定西尼罗河病毒IgM和IgG。在93名受试对象中，IgG和IgM的阳性率分别为19.4%和12.9%。在城市居民中，IgG和IgM均为阳性的比例为23.40%，而农村居民中IgG阳性率为15.22%，IgM阳性率为2.17%。针对西尼罗河病毒纯抗体的检测显示，23.7%的人感染了该病毒，8.6%的人具有与其他黄病毒发生交叉反应的抗体。结果表明，西尼罗河病毒在奥格博莫索及其周边地区传播，这可能是该地区出现类似疟疾感染的原因。
