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加拿大男性农场经营者死亡率研究:萨斯喀彻温省的癌症死亡率与农业实践

Mortality study of Canadian male farm operators: cancer mortality and agricultural practices in Saskatchewan.

作者信息

Ritter L, Wigle D T, Semenciw R M, Wilkins K, Riedel D, Mao Y

机构信息

Health Protection Branch, Health and Welfare Canada, Ottawa, Ontario.

出版信息

Med Lav. 1990 Nov-Dec;81(6):499-505.

PMID:2100765
Abstract

The present investigation involved an analysis of approximately 70,000 male Saskatchewan farm operators, a subset of the 365,000 Canadian farm operators to be investigated in the Canadian Farm Operator Mortality Study. The results of the Saskatchewan analysis indicate that during the interval studied, overall mortality among Saskatchewan farmers was 25% lower than that for all Saskatchewan men, and that, during the same time interval, the risk of death from all types of cancer was also about 25% lower among Saskatchewan farmers than to all Saskatchewan men. Although the present study indicates that overall mortality of death from cancer was 25% lower among Saskatchewan male farmers, there was a relationship between non-Hodgkin's lymphoma mortality and acres sprayed for weeds; a similar risk relationship between expenditures on fuel oil and risk of death from non-Hodgkin's lymphoma was also evident. The magnitude of risk for Saskatchewan farmers is probably greater than that reflected in the estimates in this study, due to the likelihood of misclassification of exposure. There is a particular need for further studies in this area to improve the quantification of farming-related exposures, and to study the exposure history of individuals who develop non-Hodgkin's lymphoma.

摘要

本次调查对约7万名萨斯喀彻温省男性农场经营者进行了分析,他们是加拿大农场经营者死亡率研究中计划调查的36.5万名加拿大农场经营者的一个子集。萨斯喀彻温省的分析结果表明,在所研究的时间段内,萨斯喀彻温省农民的总体死亡率比该省所有男性低25%,并且在同一时间段内,萨斯喀彻温省农民中各类癌症的死亡风险也比该省所有男性低约25%。尽管本研究表明萨斯喀彻温省男性农民的总体死亡率和癌症死亡率低25%,但非霍奇金淋巴瘤死亡率与杂草喷洒面积之间存在关联;燃油支出与非霍奇金淋巴瘤死亡风险之间也存在类似的风险关联。由于暴露情况可能分类错误,萨斯喀彻温省农民的风险程度可能高于本研究估计值所反映的程度。特别需要在该领域开展进一步研究,以改进与农业相关暴露的量化,并研究患非霍奇金淋巴瘤个体的暴露史。

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