Chirilă M, Nicolau C, Florescu L
N. Gh. Lupu Institute of Internal Medicine, Bucharest, Romania.
Med Interne. 1990 Oct-Dec;28(4):341-6.
A study was carried out in 49 flats in Bucharest inhabited by 265 persons. A quantitative analysis of fungi spores was performed as well as allergologic tests with Penicillium and Aspergillus fungi (A13), Aspergillus niger (M2), Alternaria tenuis (M1), Cladosporium herbarum (M3), Dermatophagoides pteronissinus (allergenic products supplied by the Bencard firm). The infested flats presented a high percentage of Aspergillus niger spores, particularly pathogenic. The main triggering factors for the appearance of the respiratory allergenic syndromes were found to be the conditions of humidity and the inadequate ventilation. Children are more affected by exposure to these conditions of the housing microclimate. Latent sensitization to fungi and to the Dermatophagoides pteronissinus mite in about 1/3 of the children and 1/5 of the adults represents a highly significant percentage of future candidates to bronchial asthma. A first requirement for the success of treatment in such subjects is the change of inhabiting conditions.
在布加勒斯特的49套公寓中开展了一项研究，这些公寓居住着265人。对真菌孢子进行了定量分析，并对青霉和曲霉属真菌（A13）、黑曲霉（M2）、链格孢（M1）、草本枝孢（M3）、粉尘螨（由本卡德公司提供的致敏产品）进行了过敏测试。受侵染的公寓中黑曲霉孢子的比例很高，尤其具有致病性。发现呼吸道过敏综合征出现的主要触发因素是湿度条件和通风不足。儿童更容易受到居住微气候这些条件的影响。约1/3的儿童和1/5的成年人对真菌和粉尘螨存在潜在致敏，这在未来支气管哮喘的潜在患者中占比非常高。对此类患者治疗成功的首要条件是改变居住条件。
