Exposure-response relationships between woodworking, smoking or passive smoking, and squamous cell neoplasms of the maxillary sinus.

A case-control study of squamous cell neoplasms of the maxillary sinus was performed in Hokkaido during 1982-86, with 169 cases and 338 controls matched for sex, age, and residence. The data were analyzed by a stepwise forward-selection method based on a conditional logistic-regression model without interaction terms, log-likelihood ratio tests, and chi-square tests for trend. Statistically significant linear trends were observed for associations between the risk of squamous-cell maxillary-sinus neoplasms and the duration of woodworking among men, the daily or lifetime amount of smoking among men, and the number of smokers in the household as an index of domestic exposure to cigarette smoke among women.