Grätz K W, Sailer H F, Makek M
Kieferchirurgische Klinik und Poliklinik des Universitätsspitals Zürich.
Dtsch Z Mund Kiefer Gesichtschir. 1990 Mar-Apr;14(2):122-31.
18 cases of metastases to the jaws in the last 10 years obtained from the Clinic of Maxillofacial Surgery and the Department of Pathology, University Hospital Zürich, are described. They were seen in patients with carcinoma of the breast, lung, prostate gland, uterus and seminoma of the testis. In 16 cases the metastases were situated in the mandible, in 2 cases in the maxilla. The average age of these patients was 61.6 years with no sex predilection. The initial symptoms were pain swelling. In 4 cases a pathologic fracture was diagnosed. The majority of the metastatic lesions are osteolytic in nature. The metastases were diagnosed, in average 3.3 years after diagnoses of the preliminary tumor. In 2 cases the metastases were diagnosed before the occult primary tumor. Death usually ensues 1 year after diagnoses.
本文描述了苏黎世大学医院颌面外科诊所和病理科在过去10年中收治的18例颌骨转移病例。这些病例见于乳腺癌、肺癌、前列腺癌、子宫癌和睾丸精原细胞瘤患者。16例转移灶位于下颌骨，2例位于上颌骨。这些患者的平均年龄为61.6岁，无性别倾向。初始症状为疼痛肿胀。4例诊断为病理性骨折。大多数转移瘤本质上是溶骨性的。转移瘤平均在原发肿瘤诊断后3.3年被诊断出来。2例转移瘤在隐匿性原发肿瘤之前被诊断出来。通常在诊断后1年死亡。
