Naimi N, Plancherel C, Bosser C, Jeannet M, de Moerloose P
Department of Medicine, University Hospital, Geneva, Switzerland.
Blood Coagul Fibrinolysis. 1990 Mar-Apr;1(1):5-8. doi: 10.1097/00001721-199003000-00002.
Anticardiolipin antibodies (ACA) were determined in 72 heavily transfused haemophiliacs, 43 HIV-positive and 29 HIV-negative. The presence of ACA was detected in 10 patients, all of them infected by HIV: 8 in CDC II, 1 in CDC III and 1 in CDC IV. The comparison with alterations of other laboratory markers in HIV-infected patients did not show any statistically significant difference between ACA-negative and -positive patients. In summary, ACA were found only in HIV-infected haemophiliacs. In this subgroup of patients the presence of ACA was not associated with progression to AIDS.
对72名大量输血的血友病患者进行了抗心磷脂抗体(ACA)检测,其中43名HIV阳性,29名HIV阴性。在10名患者中检测到ACA,所有这些患者均感染了HIV:8名处于疾病控制中心(CDC)II期,1名处于CDC III期,1名处于CDC IV期。与HIV感染患者其他实验室指标变化的比较显示,ACA阴性和阳性患者之间没有任何统计学上的显著差异。总之,仅在HIV感染的血友病患者中发现了ACA。在这一患者亚组中,ACA的存在与艾滋病进展无关。