School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom.
J Am Coll Cardiol. 2010 Nov 2;56(19):1535-41. doi: 10.1016/j.jacc.2010.01.076.
Acute aortic syndromes have an incidence of >30 per million per annum and a high mortality without definitive treatment. Survival may relate to the speed of diagnosis. Although pain is the most common symptom, there is a large fraction of patients in whom the diagnosis may be mistaken or overlooked. Currently, a high index of clinical suspicion is the chief prompt that diverts a patient into a definitive algorithm of imaging investigations. Although there is no point-of-care biochemical test that can be reliably used to positively identify dissection, biomarkers are available that could accelerate the diagnostic pathway and thereby expedite treatment.
急性主动脉综合征的年发病率超过每百万分之 30，若不进行明确治疗，死亡率很高。及时诊断可能与生存率相关。尽管疼痛是最常见的症状，但仍有很大一部分患者的诊断可能被误诊或忽视。目前，高度的临床怀疑是促使患者进入明确影像学检查算法的主要因素。虽然没有即时的生化检测可以可靠地用于明确诊断夹层，但生物标志物可用于加速诊断过程，从而加快治疗速度。
