Seo Jong-Kil, Shin Min Kyung, Jeong Ki-Heon, Lee Mu-Hyoung
Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, Korea.
Ann Dermatol. 2020 Dec;32(6):516-518. doi: 10.5021/ad.2020.32.6.516. Epub 2020 Nov 11.
Secondary neoplasms in nevus sebaceous can develop during adolescence and adulthood. Trichoblastoma and syringocystadenoma papilliferum are the most common benign neoplasms, but poroma is rarely reported. A 28-year-old female presented with an asymptomatic mass on the scalp. She has had a hairless lesion on the scalp since birth. A soft mass developed on that lesion four years prior. Physical examination revealed a localized 1 cm×2.5 cm-sized brownish, verrucous-surfaced plaque with a 1 cm×1 cm-sized pedunculated erythematous tumor on the scalp. We performed skin biopsy on both the plaque and tumor lesions. The histopathological findings demonstrated the plaque lesion consistent with nevus sebaceous and the tumor lesion consistent with eccrine poroma. Surgical mass excision was performed. The patient was eventually diagnosed with eccrine poroma arising within nevus sebaceous. To the best of our knowledge, there are only six reported cases on poroma arising within nevus sebaceous. Although rarely documented in the literature, it should be considered as a secondary neoplasm within nevus sebaceous.
皮脂腺痣中的继发性肿瘤可在青春期和成年期发生。毛母细胞瘤和乳头状汗管囊腺瘤是最常见的良性肿瘤，但汗孔瘤很少见报道。一名28岁女性头皮出现无症状肿块。她自出生以来头皮就有一处无毛病变。4年前该病变处出现一个柔软肿块。体格检查发现头皮有一个1厘米×2.5厘米大小的局限性褐色、表面呈疣状的斑块，以及一个1厘米×1厘米大小的带蒂红斑性肿瘤。我们对斑块和肿瘤病变均进行了皮肤活检。组织病理学检查结果显示，斑块病变符合皮脂腺痣，肿瘤病变符合小汗腺汗孔瘤。进行了肿块手术切除。该患者最终被诊断为皮脂腺痣内发生的小汗腺汗孔瘤。据我们所知，仅有6例关于皮脂腺痣内发生汗孔瘤的报道。尽管文献记载很少，但应将其视为皮脂腺痣内的继发性肿瘤。
