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墨西哥梅斯蒂索人群中的中间葡萄膜炎:眼部表现、治疗及视力预后

Pars planitis in the Mexican Mestizo population: ocular findings, treatment, and visual outcome.

作者信息

Arellanes-García Lourdes, Navarro-López Luz, Recillas-Gispert Claudia

机构信息

Inflammatory Eye Disease Clinic, 'Dr Luis Sánchez Bulnes Hospital', Asociación Para Evitar la Ceguera en México, San Lucas Coyoacán, Mexico.

出版信息

Ocul Immunol Inflamm. 2003 Mar;11(1):53-60. doi: 10.1076/ocii.11.1.53.15583.

Abstract

PURPOSE

To describe the clinical manifestations of classic pars planitis (CPP) in Mexican patients. We report here the most frequent complications, medical and surgical treatment, and visual prognosis.

MATERIAL AND METHODS

A retrospective, descriptive case series examined the clinical features, complications, and treatment (medical and surgical) of CPP patients seen at the Inflammatory Eye Disease Clinic from January 1990 to September 1999.

RESULTS

One hundred and sixty patients met inclusion criteria for the study. Mean age at presentation was 10 years and males were more frequently affected. Both eyes were affected in 84.4% of the cases. The most frequent complaint was decreased visual acuity. Initial visual acuity (VA) ranged from no light perception to 20/20 (mean 20/50), and mean final VA was 20/30. The most frequent clinical manifestations were vitritis (99.7%), snowballs (99.3%), retinal vasculitis (89.2%), and snowbanks (63.1%). The most common complications were cystoid macular edema (63.4%) and cataract (47.5%). Periocular corticosteroids were used in 97.5% of cases, systemic corticosteroids in 68.1%, and other immunosuppressive drugs in 21.3%.

CONCLUSIONS

CPP in the Mexican population is more frequent in males and usually presents in patients less than 14 years of age. It is typically bilateral, and the most common symptom is decreased visual acuity. The most important clinical findings are located in the vitreous and retina. Cataract and cystoid macular edema are the most frequent complications. Treatment comprises periocular and systemic corticosteroids or other immunosuppressive drugs.

摘要

目的

描述墨西哥患者中典型的周边部葡萄膜炎(CPP)的临床表现。我们在此报告其最常见的并发症、药物及手术治疗方法以及视力预后情况。

材料与方法

一项回顾性描述性病例系列研究,对1990年1月至1999年9月在炎症性眼病诊所就诊的CPP患者的临床特征、并发症及治疗(药物和手术)情况进行了检查。

结果

160例患者符合该研究的纳入标准。就诊时的平均年龄为10岁,男性更易受累。84.4%的病例双眼均受累。最常见的主诉是视力下降。初始视力(VA)范围从无光感到20/20(平均20/50),最终平均视力为20/30。最常见的临床表现为玻璃体炎(99.7%)、雪球样混浊(99.3%)、视网膜血管炎(89.2%)和雪堤样改变(63.1%)。最常见的并发症是黄斑囊样水肿(63.4%)和白内障(47.5%)。97.5%的病例使用了眼周皮质类固醇,68.1%使用了全身皮质类固醇,21.3%使用了其他免疫抑制药物。

结论

墨西哥人群中的CPP在男性中更为常见,通常发生在14岁以下的患者中。它通常是双侧的,最常见的症状是视力下降。最重要的临床发现位于玻璃体和视网膜。白内障和黄斑囊样水肿是最常见的并发症。治疗包括眼周和全身皮质类固醇或其他免疫抑制药物。

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