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开发一种多途径概率健康风险评估模型,用于评估在室内游泳池中暴露于三氯甲烷的游泳者的健康风险。

Development of a multi-pathway probabilistic health risk assessment model for swimmers exposed to chloroform in indoor swimming pools.

机构信息

Department of Occupational Safety and Hygiene, Fooyin University, 151 Chin-Hsueh Road, Ta-Liao Hsiang, Kaohsiung Hsien 831, Taiwan.

出版信息

J Hazard Mater. 2011 Jan 30;185(2-3):1037-44. doi: 10.1016/j.jhazmat.2010.10.011. Epub 2010 Oct 12.

Abstract

For swimmers, exposure to chloroform, a probable carcinogen, in indoor swimming pools can be through different pathways such as ingestion, dermal absorption, inhalation during swimming, and inhalation during resting. In order to evaluate health risk results from excessive exposure to chloroform, concentrations of chloroform in pool water were first collected and analyzed. Then, a two-layer model is used, which is capable of estimating the concentrations of chloroform in the boundary layer adjacent to the water surface and the concentrations of chloroform in indoor swimming pool air. The use of stratification model is important for estimating the risks for swimmers since they are exposed to these kinds of situations while performing swimming and resting in indoor swimming pools environment. The incremental lifetime cancer risk (ILCR) was then estimated using the multi-pathway exposure model. The results showed that the 95th percentile of ILCRs calculated for male and female swimmers were 2.80 × 10(-4) and 2.47 × 10(-4), respectively. The major exposure routes were found to be inhalation during swimming which contributes to more than 99% of the total health risk. Our study suggested that to protect swimmers from excessive exposure to chloroform, alternative methods or processes of disinfection should be considered for swimming pool managers.

摘要

对于游泳者来说,在室内游泳池中可能会通过不同的途径接触到氯仿,一种可能的致癌物质,例如摄入、皮肤吸收、游泳时吸入以及休息时吸入。为了评估因过度暴露于氯仿而产生的健康风险,首先收集和分析了泳池水中的氯仿浓度。然后,使用两层模型,该模型能够估算与水面相邻的边界层中的氯仿浓度以及室内游泳池空气中的氯仿浓度。由于游泳者在室内游泳池环境中进行游泳和休息时会暴露于这些情况,因此分层模型的使用对于估计游泳者的风险非常重要。然后,使用多途径暴露模型估算了增量终生癌症风险(ILCR)。结果表明,男性和女性游泳者的 ILCR 第 95 百分位数分别计算为 2.80×10(-4)和 2.47×10(-4)。主要暴露途径是游泳时的吸入,其导致的健康风险超过总风险的 99%。我们的研究表明,为了保护游泳者免受氯仿的过度暴露,游泳池管理者应考虑替代的消毒方法或工艺。

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