Department of Pharmacology, Sri Devaraj urs Medical College, Tamaka, Kolar, Karnataka, India.
Food Chem Toxicol. 2011 Jan;49(1):248-50. doi: 10.1016/j.fct.2010.10.026. Epub 2010 Oct 29.
The global problem of acute poisoning has steadily increased over the past few years. It is an important cause of morbidity and mortality in developing countries. Better preventive and management strategies can be developed if the incidence and pattern of acute poisoning is known. The study aims at analyzing the pattern, cause and mortality rate of poisoning. The study was conducted in a rural area in South India. This retrospective study was conducted from January 2003-December 2003. The data was analysed using descriptive statistics. Out of the 225 cases 139 were males and 86 females. Poisoning was common in the age group of 21-30 years which was 84 cases and 11-20 years was 73 cases. The poisons consumed were as follows: Organophosphorous 135 cases, aluminum and zinc phosphide 50 cases, phenobarbitone 18 cases, benzodiazepines 7 cases, paracetamol 2 cases, miscellaneous 13 cases. 94% were suicides and 6% accidental. Mortality rate was 12.8%. Establishment of strict policies against the sale and availability of pesticides and over the counter drugs is an effective way to control organophosphorous and drug poisoning.
在过去的几年中,全球急性中毒问题稳步增加。这是发展中国家发病率和死亡率的重要原因。如果了解急性中毒的发病率和模式,则可以制定更好的预防和管理策略。本研究旨在分析中毒的模式、原因和死亡率。该研究在印度南部的一个农村地区进行。这是一项回顾性研究,时间为 2003 年 1 月至 12 月。使用描述性统计数据对数据进行分析。在 225 例中,男性 139 例,女性 86 例。中毒在 21-30 岁年龄组中很常见,有 84 例,11-20 岁年龄组中有 73 例。消耗的毒物如下:有机磷 135 例,铝和锌磷化氢 50 例,苯巴比妥 18 例,苯二氮䓬类 7 例,扑热息痛 2 例,其他 13 例。94%为自杀,6%为意外。死亡率为 12.8%。制定严格的政策禁止销售和提供农药和非处方药是控制有机磷和药物中毒的有效方法。