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与儿童期精神障碍相关的经济成本和基于偏好的健康相关生活质量结果。

Economic costs and preference-based health-related quality of life outcomes associated with childhood psychiatric disorders.

机构信息

Warwick Clinical Trials Unit, University of Warwick, Coventry CV4 7AL, UK.

出版信息

Br J Psychiatry. 2010 Nov;197(5):395-404. doi: 10.1192/bjp.bp.110.081307.

Abstract

BACKGROUND

Childhood psychiatric disorders may have deleterious consequences through childhood and into adulthood.

AIMS

To estimate costs and preference-based health-related quality of life outcomes (health utilities) associated with a broad range of childhood psychiatric disorders during the eleventh year of life.

METHOD

Participants in a whole-population study of extremely preterm children and term-born controls (EPICure) undertook psychiatric assessment using the Development and Well Being Assessment (DAWBA) and the Kaufman-Assessment Battery for Children. Questionnaires completed by parents and teachers described the children's utilisation of health, social and education services during the eleventh year of life. Parents also described their child's health status using the Health Utilities Index Mark 2 and Mark 3 health status classification systems. Descriptive and multiple regression techniques were used to explore the association between psychiatric disorders and economic outcomes.

RESULTS

The study presents detailed costs and health utilities associated with psychiatric disorders for the preterm population, term-born population and pooled study population, following appropriate controls.

CONCLUSIONS

The results of this study should be used to inform future economic evaluations of interventions aimed at preventing childhood psychiatric disorders or alleviating their effects. Further research is required that identifies, measures and values the longer-term economic impacts of these disorders in a valid and reliable manner.

摘要

背景

儿童期精神障碍可能会对儿童期和成年期产生有害影响。

目的

在生命的第十一年评估广泛的儿童期精神障碍相关的成本和基于偏好的健康相关生活质量(健康效用)结果。

方法

在一项对极早产儿和足月出生对照的全人群研究(EPICure)中,参与者使用发育和幸福感评估(DAWBA)和 Kaufman 儿童评估量表进行精神科评估。父母和教师填写的问卷描述了儿童在生命的第十一年期间对健康、社会和教育服务的利用情况。父母还使用健康效用指数标记 2 和标记 3 健康状况分类系统描述了孩子的健康状况。描述性和多元回归技术用于探索精神障碍与经济结果之间的关联。

结果

本研究针对早产儿人群、足月出生人群和汇总研究人群,在进行适当对照后,呈现了与精神障碍相关的详细成本和健康效用。

结论

本研究的结果应用于为预防儿童期精神障碍或减轻其影响的干预措施的未来经济评估提供信息。需要进一步的研究,以有效和可靠的方式确定、衡量和评估这些障碍的长期经济影响。

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