Morris Winston E, Venzano Agustín J, Craig María Isabel, Diodati Julián A, Funes Daniel, Elizondo Ana, Mercado Elsa, Capellino Felix, Delgado Fernando, Blanco-Viera Javier
Veterinary and Agronomic Research Centre, National Institute of Agricultural Technology, Castelar, Argentina.
Can Vet J. 2010 Aug;51(8):877-80.
This study reports 3 cases of spontaneous papillomavirus infection in 1-week-old calves. Thickening of the omasum and abomasum wall, with acute inflammation, necrosis, ulceration, and neoplastic changes were seen in 1 calf. In the other 2, small papillomas were observed in the omasal mucosa, exhibiting proliferation of the parakeratinized epithelium. Papillomavirus antigens were detected by immunohistochemistry and virus-like particles were seen through electron microscopy.
本研究报告了1周龄犊牛自发性乳头瘤病毒感染的3个病例。在1头犊牛中观察到皱胃和真胃壁增厚,伴有急性炎症、坏死、溃疡和肿瘤性变化。在另外2头犊牛中,在皱胃黏膜中观察到小的乳头瘤,表现为不全角化上皮增生。通过免疫组织化学检测到乳头瘤病毒抗原,并通过电子显微镜观察到病毒样颗粒。