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GA² LEN/EAACI 变应原特异性免疫治疗过敏性鼻炎和哮喘实用指南。

GA² LEN/EAACI pocket guide for allergen-specific immunotherapy for allergic rhinitis and asthma.

机构信息

Department of Dermatology and Allergy, Charité- Universitätsmedizin Berlin, Berlin, Germany.

出版信息

Allergy. 2010 Dec;65(12):1525-30. doi: 10.1111/j.1398-9995.2010.02474.x. Epub 2010 Sep 7.

DOI:10.1111/j.1398-9995.2010.02474.x
PMID:21039596
Abstract

This pocket guide is the result of a consensus reached during several GA(2) LEN and EAACI meetings. The aim of the current pocket guide is to offer a comprehensive set of recommendations on the use of immunotherapy in allergic rhinoconjunctivitis and asthma in daily practice. This pocket guide is meant to give simple answers to the most frequent questions of practitioners in Europe, including 'practising allergists', general practitioners and any other physicians with special interest in allergen-specific immunotherapy (SIT). It is not a long or detailed scientific review of the topic. However, the recommendations in this pocket guide were compiled following an in-depth review of existing guidelines and publications, including the 1998 EAACI position paper, the 1998 WHO Position Paper on SIT and the 2001 Allergic Rhinitis and its Impact on Asthma (ARIA). It is also based on the ARIA update 2008 (prepared in collaboration with GA(2) LEN), the 'Sub-lingual Immunotherapy: WAO Position Paper 2009' (from the World Allergy Organisation) and the Methodology paper of ARIA. The recommendations cover patient selection, allergen extract to be used, route of administration of SIT (in particular, sublingual and subcutaneous immunotherapy), and necessary precautions to be followed in using SIT.

摘要

本袖珍指南是在多次 GA(2)LEN 和 EAACI 会议达成共识的基础上编写而成的。目前这本袖珍指南的目的是为过敏鼻炎和哮喘的免疫治疗在日常实践中的应用提供一套全面的建议。本袖珍指南旨在为欧洲的从业者,包括“执业变态反应学家”、全科医生和任何对过敏原特异性免疫治疗(SIT)特别感兴趣的其他医生,提供对最常见问题的简单答案。这不是对该主题的长篇或详细的科学综述。然而,本袖珍指南中的建议是在对现有指南和出版物进行深入审查的基础上制定的,其中包括 1998 年 EAACI 立场文件、1998 年世卫组织 SIT 立场文件和 2001 年过敏性鼻炎及其对哮喘的影响(ARIA)。它还基于 2008 年 ARIA 更新(与 GA(2)LEN 合作编写)、“舌下免疫疗法:WAO 2009 立场文件”(来自世界过敏组织)和 ARIA 的方法学文件。这些建议涵盖了患者选择、要使用的过敏原提取物、SIT 的给药途径(特别是舌下和皮下免疫疗法),以及使用 SIT 时必须遵循的必要预防措施。

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