Oculoplastic and Orbital Surgery Service, Wills Eye Institute, Philadelphia, Pennsylvania 19107, USA.
Clin Exp Ophthalmol. 2011 Jan;39(1):65-83; quiz 92-3. doi: 10.1111/j.1442-9071.2010.02422.x. Epub 2011 Jan 31.
The diagnosis and management of periocular cutaneous malignancies are essential components of an ophthalmologist's practice. Skin cancers comprise nearly one-third of newly diagnosed malignancies. Furthermore, the incidence of skin cancer appears to be increasing. Multiple treatment modalities exist for periocular cutaneous malignancy. Surgical extirpation, often with the combined expertise of a Mohs micrographic surgeon, is typically the first line therapy and is often curative in the periocular region, depending on a variety of factors, including tumour histology, specific location, depth of invasion and surgical technique. However, there are instances where a less invasive, non-surgical treatment option is warranted, including patients who are poor surgical risks or those with diffuse disease. The purpose of this article is to review the literature and describe the non-surgical treatment options, indications and efficacies for non-melanoma primary eyelid malignancies.
眼周皮肤恶性肿瘤的诊断和治疗是眼科医生临床实践的重要组成部分。皮肤癌约占新诊断恶性肿瘤的三分之一。此外，皮肤癌的发病率似乎呈上升趋势。眼周皮肤恶性肿瘤有多种治疗方法。手术切除通常是第一线治疗方法，通常在眼周区域具有治愈性，但取决于多种因素，包括肿瘤组织学、特定位置、侵袭深度和手术技术。然而，在某些情况下，需要采用侵入性较小的非手术治疗方法，包括手术风险较高的患者或患有弥漫性疾病的患者。本文旨在回顾文献，描述非黑色素瘤原发性眼睑恶性肿瘤的非手术治疗选择、适应证和疗效。
