Fundacio Puigvert -Pediatric Urology, Barcelona, Spain.
BJU Int. 2011 Jun;107(11):1812-6. doi: 10.1111/j.1464-410X.2010.09796.x. Epub 2010 Oct 29.
Therapy (case series).
To report our experience of testicular tumours in children aged≤13 years, including our experience with testis-sparing surgery.
A retrospective study was performed of 15 patients with testicular tumours aged≤13 years who presented at our centre between 1984 and 2008. The use of testis-preserving surgery according to indication was investigated and outcomes were recorded.
The clinical presentation was increased testicular size with a palpable mass in 80% of the cases. All 15 patients underwent surgery. The tumour was benign in 12 (80%) patients and malignant in three (20%) patients. Organ-preserving surgery was planned and achieved in 11 patients (73%). Pathology of the tumourectomy specimens disclosed benign tumours in all cases: four epidermoid cysts, two teratomas, one juvenile granulosa cell tumour, one haemangioma, one lipoma, one fibrous hamartoma and one splenogonadal fusion. In four patients who underwent radical orchiectomy, pathology identified one yolk sac tumour (stage I), two mixed germ cell tumours and one gonadoblastoma.
In children, most testicular tumours are benign, especially before puberty. A testis-sparing procedure should be performed in children with a palpable testicular mass and negative tumour markers. The lesion, however, should be thoroughly excised to avoid recurrences.
治疗（病例系列）。
4。本领域已知内容：儿童睾丸肿瘤非常罕见。从历史上看，这些肿瘤大多被认为是恶性的，但最近的研究表明，良性病变，特别是畸胎瘤，比以前认为的更为常见。该年龄段的睾丸肿瘤传统上采用腹股沟根治性睾丸切除术治疗，但鉴于良性肿瘤的频率较高，提出了更保守的治疗方法。在儿童中，大多数睾丸肿瘤是良性的，尤其是在青春期之前。对于可触及睾丸肿块且肿瘤标志物阴性的儿童，应进行保留睾丸的手术。
报告我们在≤13 岁儿童睾丸肿瘤方面的经验，包括保留睾丸手术的经验。
对 1984 年至 2008 年期间在我们中心就诊的≤13 岁睾丸肿瘤患儿 15 例进行回顾性研究。根据适应证探讨保留睾丸手术的应用，并记录结果。
80%的病例表现为睾丸增大伴可触及肿块。所有 15 例患者均接受手术治疗。12 例（80%）患者的肿瘤为良性，3 例（20%）患者为恶性。11 例（73%）患者计划并完成了保留器官的手术。肿瘤切除术标本的病理显示所有病例均为良性肿瘤：表皮样囊肿 4 例，畸胎瘤 2 例，幼年颗粒细胞瘤 1 例，血管瘤 1 例，脂肪瘤 1 例，纤维性错构瘤 1 例，脾性腺融合 1 例。在接受根治性睾丸切除术的 4 例患者中，病理检查发现 1 例卵黄囊瘤（Ⅰ期）、2 例混合性生殖细胞瘤和 1 例性腺母细胞瘤。
在儿童中，大多数睾丸肿瘤是良性的，尤其是在青春期之前。对于可触及睾丸肿块且肿瘤标志物阴性的儿童，应进行保留睾丸的手术。然而，为了避免复发，应彻底切除病变。
