van de Kerkhof Rolf M, Godefrooij Merijn B, Wouda Paul J, Vening Robert A, Dinant Geert-Jan, Spigt Mark G
Stichting Gezondheidscentra Eindhoven, Gezondheidscentrum Woensel, the Netherlands.
Ned Tijdschr Geneeskd. 2010;154:A1860.
Design and implementation of a preventative screening programme for cardiometabolic risk assessment in a medium-sized general practice. Description of the response rate and number of detected diseases to be treated.
Questionnaire and observational research.
All registered patients aged 40 to 75 years without prior cardiometabolic disease (cardiovascular diseases, diabetes and renal disorders) (n=1704) received a written invitation to participate in a preventative screening programme. During a maximum of 3 sequential screening steps the risk for cardiometabolic disease for each participant was determined. Based on their outcome, participants were offered treatment when necessary. The number of patients who completed each of the steps as well as the number of detected disorders were registered.
In total 1270 patients (75%) returned an initial screening questionnaire. Based on the information provided in this questionnaire 952 patients were invited for an additional examination at the general practice. In 145 participants (11% of 1270) at least one condition was diagnosed that needed either treatment or follow-up according to the prevailing Dutch practice guidelines, such as elevated risk for cardiovascular diseases, isolated systolic hypertension, diabetes mellitus, suspected familiar hypercholesterolaemia or renal disorders.
The response-rate as well as the number of newly diagnosed cases demonstrate that it is quite feasible to screen for cardiometabolic disorders in a primary healthcare centre. Follow-up studies are needed to assess the long-term health effects and efficiency of the preventative screening programme.
在一家中等规模的普通诊所设计并实施一项用于心血管代谢风险评估的预防性筛查计划。描述应答率及所检出需治疗疾病的数量。
问卷调查与观察性研究。
所有年龄在40至75岁、无心血管代谢疾病（心血管疾病、糖尿病和肾脏疾病）既往史的注册患者（n = 1704）收到一份书面邀请，参与一项预防性筛查计划。在最多3个连续的筛查步骤中，确定每位参与者患心血管代谢疾病的风险。根据结果，必要时为参与者提供治疗。记录完成每个步骤的患者数量以及所检出疾病的数量。
共有1270名患者（75%）返回了初始筛查问卷。根据该问卷提供的信息，952名患者被邀请到普通诊所进行进一步检查。在145名参与者（占1270名的11%）中，根据现行荷兰实践指南，至少诊断出一种需要治疗或随访的疾病，如心血管疾病风险升高、单纯收缩期高血压、糖尿病、疑似家族性高胆固醇血症或肾脏疾病。
应答率和新诊断病例数表明，在初级医疗保健中心筛查心血管代谢疾病是相当可行的。需要进行后续研究以评估预防性筛查计划的长期健康影响和效率。
