Robinson Thomas N, Matheson Donna M, Kraemer Helena C, Wilson Darrell M, Obarzanek Eva, Thompson Nikko S, Alhassan Sofiya, Spencer Tirzah R, Haydel K Farish, Fujimoto Michelle, Varady Ann, Killen Joel D
Division of General Pediatrics and Stanford Prevention Research Center, Stanford University School of Medicine, 1070 Arastradero Road, Palo Alto, CA 94304, USA.
Arch Pediatr Adolesc Med. 2010 Nov;164(11):995-1004. doi: 10.1001/archpediatrics.2010.197.
To test a 2-year community- and family-based obesity prevention program for low-income African American girls: Stanford GEMS (Girls' health Enrichment Multi-site Studies).
Randomized controlled trial with follow-up measures scheduled at 6, 12, 18, and 24 months.
Low-income areas of Oakland, California.
African American girls aged 8 to 10 years (N=261) and their parents or guardians.
Families were randomized to one of two 2-year, culturally tailored interventions: (1) after-school hip-hop, African, and step dance classes and a home/family-based intervention to reduce screen media use or (2) information-based health education.
Changes in body mass index (BMI).
Changes in BMI did not differ between groups (adjusted mean difference [95% confidence interval] = 0.04 [-0.18 to 0.27] per year). Among secondary outcomes, fasting total cholesterol level (adjusted mean difference, -3.49 [95% confidence interval, -5.28 to -1.70] mg/dL per year), low-density lipoprotein cholesterol level (-3.02 [-4.74 to -1.31] mg/dL per year), incidence of hyperinsulinemia (relative risk, 0.35 [0.13 to 0.93]), and depressive symptoms (-0.21 [-0.42 to -0.001] per year) decreased more among girls in the dance and screen time reduction intervention. In exploratory moderator analysis, the dance and screen time reduction intervention slowed BMI gain more than health education among girls who watched more television at baseline (P = .02) and/or those whose parents or guardians were unmarried (P = .01).
A culturally tailored after-school dance and screen time reduction intervention for low-income, preadolescent African American girls did not significantly reduce BMI gain compared with health education but did produce potentially clinically important reductions in lipid levels, hyperinsulinemia, and depressive symptoms. There was also evidence for greater effectiveness in high-risk subgroups of girls.
对一项针对低收入非裔美国女孩开展的为期两年的社区及家庭肥胖预防项目——斯坦福女孩健康强化多地点研究(Stanford GEMS)进行测试。
随机对照试验,在6个月、12个月、18个月和24个月安排随访测量。
加利福尼亚州奥克兰的低收入地区。
8至10岁的非裔美国女孩(N = 261)及其父母或监护人。
家庭被随机分配到两种为期两年、针对文化定制的干预措施之一:(1)课后嘻哈舞、非洲舞和踢踏舞课程以及一项减少屏幕媒体使用的家庭干预措施;或(2)基于信息的健康教育。
体重指数(BMI)的变化。
两组之间BMI的变化无差异(调整后平均差异[95%置信区间] = 每年0.04[-0.18至0.27])。在次要结局中,舞蹈和减少屏幕时间干预组女孩的空腹总胆固醇水平(调整后平均差异,每年-3.49[95%置信区间,-5.28至-1.70]mg/dL)、低密度脂蛋白胆固醇水平(每年-3.02[-4.74至-1.31]mg/dL)、高胰岛素血症发病率(相对风险,0.35[0.13至0.93])和抑郁症状(每年-0.21[-0.42至-0.001])下降幅度更大。在探索性调节分析中,对于基线时看电视较多的女孩(P = 0.02)和/或其父母或监护人未婚的女孩(P = 0.01),舞蹈和减少屏幕时间干预措施比健康教育更能减缓BMI的增加。
与健康教育相比,针对低收入青春期前非裔美国女孩的文化定制课后舞蹈和减少屏幕时间干预措施并未显著降低BMI的增加,但确实在脂质水平、高胰岛素血症和抑郁症状方面产生了潜在的临床重要降低。此外,有证据表明该干预措施在高风险女孩亚组中更有效。