1,2-O-(2,2,2-三氯亚乙基)衍生物的 Knoevenagel-Doebner 反应。D-吡喃葡萄糖和 D-吡喃甘露糖。
The Knoevenagel-Doebner reaction on 1,2-O-(2,2,2-trichloroethylidene) derivatives of D-gluco- and D-manno-furanose.
机构信息
Chemistry Department, Faculty of Science, Ege University, Bornova, İzmir 35100, Turkey.
出版信息
Molecules. 2010 Oct 29;15(11):7724-31. doi: 10.3390/molecules15117724.
Abstract
The synthesis of new α,β-unsaturated furanuronic acid derivatives of α-gluco-, β-gluco- and β-manno-chloraloses via a convenient one pot procedure using the Knoevenagel-Doebner reaction approach are described. The dialdofuranose derivatives were reacted with malonic acid under Knoevenagel-Doebner reaction conditions and (E)-α,β-unsaturated furanuronic acid derivatives were obtained.
摘要
通过 Knoevenagel-Doebner 反应方法，以方便的一锅法合成了新的α-葡萄糖基、β-葡萄糖基和β-甘露基氯醛糖的α，β-不饱和呋喃糖酸衍生物。二醛呋喃糖衍生物与丙二酸在 Knoevenagel-Doebner 反应条件下反应，得到（E）-α，β-不饱和呋喃糖酸衍生物。
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