Chemistry Department, Faculty of Science, Ege University, Bornova, İzmir 35100, Turkey.
Molecules. 2010 Oct 29;15(11):7724-31. doi: 10.3390/molecules15117724.
The synthesis of new α,β-unsaturated furanuronic acid derivatives of α-gluco-, β-gluco- and β-manno-chloraloses via a convenient one pot procedure using the Knoevenagel-Doebner reaction approach are described. The dialdofuranose derivatives were reacted with malonic acid under Knoevenagel-Doebner reaction conditions and (E)-α,β-unsaturated furanuronic acid derivatives were obtained.
通过 Knoevenagel-Doebner 反应方法，以方便的一锅法合成了新的α-葡萄糖基、β-葡萄糖基和β-甘露基氯醛糖的α，β-不饱和呋喃糖酸衍生物。二醛呋喃糖衍生物与丙二酸在 Knoevenagel-Doebner 反应条件下反应，得到（E）-α，β-不饱和呋喃糖酸衍生物。
